彩色多普勒超声对脑梗死患者股动脉血流动力学的研究

目的　应用彩色多普勒超声研究脑梗死患者股动脉内-中膜厚度及血流动力学变化,以探讨脑梗死与股动脉硬化的关系。方法　对3 0例脑梗死患者及2 5例正常人的股动脉行二维及彩色多普勒超声检查,观察股动脉内膜回声及有无粥样硬化斑块,测量内-中膜厚度( IMT)和脉冲多普勒血流频谱参数,包括收缩期峰值速度( Vs)、舒张早期峰值速度( Vd)、舒张早期多普勒频谱血流积分( VTId)、阻力指数( RI)、动脉波传递时间( TR- Vs)。结果　( 1 )脑梗死组股动脉IMT( 0 .72±0 .1 4 ) mm]明显大于对照组( 0 .5 9±0 .0 9) mm,P<0 .0 5 ];( 2 )脑梗死组股动脉斑块发生率高于对照组( P<0 .0 5 ) ;( 3 )脑梗死组股动脉Vd、VTId、TR- Vs/ T均小于对照组( P<0 .0 5 ) ;Vs、RI两组之间差别无显著性意义( P>0 .0 5 )。结论　脑梗死患者股动脉IMT增厚,粥样硬化斑块发生率增加,VTId、TR- Vs/ T减低。VTId、TR- Vs/ T可作为评价外周动脉硬化的新指标

Color Doppler Ultrasonographic Assessment of Femoral Artery IMT and Hemodynamics in Patients with Cerebral Infarction

Objective To study the change of the hemodynamics and intima-media thickness(IMT) of femoral artery(FA) in patients with cerebral infarction utilized color Doppler ultrasonography.Methods FA in thirty patients and twenty-five healthy adults were examined with two-dimensional and color Doppler ultrasonography.We observed the echo of the intima-media and measured intima-media thickness(IMT),spectral waves and hemodynamic parameters including the systolic peak velocity,diastolic peak velocity,integrity of diastolic wave,resistive index and ratio of time from R peak of ECG to the start of systolic spectrum and the time of one cardiac circle(T_(R-Vs)/T).Results Compared with the control group,the patient group had significantly thicker IMT(P<0.05),higher occurrence rate of atherosclerosis plaque and smaller V_d,VTI_d and T_(R-Vs)/T of FA(P<0.05).There was no significant difference of V_s and RI between the two groups(P>0.05).Conclusions IMT,V_d,VTI_d and T_(R-Vs)/T can be used as the new indices to evaluate the atherosclerosis of peripheral arteries.