H型高血压与急性冠脉综合征的相关性研究

目的:探讨H型高血压与急性冠脉综合征(ACS)的相关性。方法:选取157例原发性高血压合并急性冠脉综合征患者为研究对象,按照Hcy水平不同,将其分为H型高血压组(Hcy≥10μmol/L)96例和单纯性高血压组(Hcy<10μmol/L)61例,比较H型高血压组与单纯高血压组急性冠脉综合征所占比例数以及比较H型高血压组的不稳定型心绞痛、非ST段抬高型心肌梗死、ST段抬高型心肌梗死患者的Hcy水平。结果:H型高血压组与单纯高血压组相比,不稳定型心绞痛、非ST段抬高型心肌梗死、ST段抬高型心肌梗死患者比例,差异无统计学意义(P>0.05),H型高血压组急性心肌梗死(AMI)患者的比例显著高于单纯性高血压组(P<0.05)。不稳定型心绞痛组、非ST段抬高型心肌梗死组、ST段抬高型心肌梗死组3组间血清Hcy水平比较,差异无统计学意义(P>0.05),而该3组血清Hcy水平分别同对照组比较,明显高于对照组,差异有统计学意义(P<0.05)。结论:H型高血压与ACS密切相关,可通过降低Hcy水平,进而降低心血管事件的发生率。

Coherence Research on the Type H Hypertension and Acute Coronary Syndrome

Objective:To discuss the relativity of type H hypertension and acute coronary syndrome.Methods:157 cases of type H hypertension combine with acute coronary syndrome were selected,according to different level of Hcy,divided into type H hypertension group(Hcy ≥10 umol/L) 96 cases and 61 cases essential hypertension group(Hcy <10 umol/L.Compare the propotion of acute coronary syndrome in type H hypertension group and essential hypertension group,and unstable angina pectoris 、the Hcy level of informal ST-segment elevation myocardial infarction and ST-segment elevation myocardial infarction.Results:There was no significant difference between two groups(P>0.05) in unstable angina pectoris 、the Hcy level of informal ST-segment elevation myocardial infarction and ST-segment elevation myocardial infarction.acute myocardial infarction in type H hypertension group were much higher than in essential hypertension group(P<0.05).There was no significant difference between three groups of unstable angina pectoris 、informal ST-segment elevation myocardial infarction and ST-segment elevation myocardial infarction in the Hcy level(P<0.05),Hcy level in serum of three groups were more higher than control group(P<0.05).Conclusion:Type H hypertension was closely related with ACS,by means of reduce Hcy level,then reduce cardiovascular incidence.