鼻塞式双相气道正压通气治疗先天性喉喘鸣合并新生儿肺炎患儿的效果

目的:观察鼻塞式双相气道正压通气(BiPAP)治疗先天性喉喘鸣合并新生儿肺炎患儿的效果。方法:选取82例先天性喉喘鸣合并新生儿肺炎患儿为研究对象,采用随机数字表法分为观察组和对照组各41例,对照组给予自主呼吸状态下持续气道内正压(CPAP)治疗,观察组给予鼻塞式BiPAP治疗;观察两组血气分析指标动脉血二氧化碳分压(PaCO₂)、动脉血氧分压(PaO₂)]水平、动脉血pH值、吸入氧浓度(FiO₂)、通气时间、氧疗时间、抗感染时间、住院时间及并发症发生率。结果:治疗后,两组FiO₂、PaCO₂水平均低于治疗前,且观察组低于对照组,两组动脉血pH值、PaO₂水平均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05);观察组通气时间、氧疗时间、抗感染治疗时间和住院时间均短于对照组,差异有统计学意义(P<0.05);观察组并发症发生率为9.76%,低于对照组的26.83%,差异有统计学意义(P<0.05)。结论:鼻塞式BiPAP通气治疗先天性喉喘鸣合并新生儿肺炎患儿可改善血气分析指标水平,提高动脉血pH值,缩短通气时间、氧疗时间、抗感染治疗时间和住院时间,降低FiO₂和并发症发生率,优于自主呼吸下CPAP治疗效果。

Effects of nasal tampon style biphasic positive airway pressure ventilation on congenital laryngeal stridor and neonatal pneumonia

Objective:To observe effect of nasal tampon style biphasic positive airway pressure ventilation(BiPAP)in treatment of congenital laryngeal stridor and neonatal pneumonia.Methods:82 children with congenital laryngeal stridor and neonatal pneumonia were selected as the research objects,and were divided into observation group and control group by using the random number table method,41 cases in each group.The control group was given continuous positive airway pressure(CPAP)treatment under spontaneous breathing,while the observation group was given nasal tampon style BiPAP treatment.The blood gas analysis indicatorsarterial partial pressure of carbon dioxide(PaCO₂),arterial partial pressure of oxygen(PaO₂)],pH,inhaled oxygen concentration(FiO₂)levels,the ventilation time,the oxygen therapy time,the anti-infection time,the hospitalization time,and the incidence of complications of the two groups were observed.Results:After the treatment,the levels of FiO₂and PaCO₂in the two groups were lower than before the treatment,and those of the observation group were lower than those of the control group;the arterial blood pH and PaO₂levels of the two groups were higher than before the treatment,and those of the observation group were higher than those of the control group;and the differences were statistically significant(P<0.05).The ventilation time,the oxygen therapy time,the anti-infection time and the hospitalization time of the observation group were shorter than those of the control group,and the differences were statistically significant(P<0.05).Further,the complication rate in the observation group was 9.76%,which was lower than 26.83%in the control group,and the difference was statistically significant(P<0.05).Conclusions:Nasal tampon style BiPAP ventilation in the treatment of the children with congenital laryngeal stridor combined with neonatal pneumonia can improve the blood gas analysis index levels,increase arterial blood pH,shorten the ventilation time,the oxygen therapy time,the anti-infection treatment time and the hospitalization time,reduce the FiO₂levels and incidence of complications.Moreover,it is superior to CPAP treatment under spontaneous breathing.