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动态检测细胞因子水平在病毒性心肌炎各期的临床价值
引用本文:刘雪玲,王焱,虞勇.动态检测细胞因子水平在病毒性心肌炎各期的临床价值[J].中国现代医药杂志,2008,10(7):50-52.
作者姓名:刘雪玲  王焱  虞勇
作者单位:1. 北京世纪坛医院心内科,100038
2. 广东医学院附属医院心内科
3. 上海市病毒性心肌炎研究室
摘    要:目的探讨细胞因子的动态水平在病毒性心肌炎各期的临床价值。方法采用放免法、化学比色法及酶联免疫法检测31例病毒性心肌炎患者和32例正常人的血清肿瘤坏死因子(TNF-a)、一氧化氮(NO)、白细胞介素-2,6(IL-2,IL-6)的动态水平。结果四种细胞因子的血清水平在病毒性心肌炎组均明显高于正常对照组,并呈急性期〉亚急性期〉恢复期。结论肿瘤坏死因子-a和一氧化氮、白介素均参与病毒性心肌炎的心肌细胞炎性损伤过程,其浓度变化可能具有双重作用。

关 键 词:肿瘤坏死因子  一氧化氮  白细胞介素-2、6  病毒性心肌炎

Dynamic change of serum cytokines levels in patients with virus myocarditis and its clinical value
Liu Xueling,Wang Yan,Yu Yong.Dynamic change of serum cytokines levels in patients with virus myocarditis and its clinical value[J].Modern Medicine Journal of China,2008,10(7):50-52.
Authors:Liu Xueling  Wang Yan  Yu Yong
Affiliation:Liu Xueling,Wang Yan,Yu Yong.Department of Cardiology,Beijing Shijitan Hospital,Beijing 100038
Abstract:Objective To explore the clinical value of dynamic change of serum cytokines levels in patients with virus myocarditis.Methods The serum levels of tumor necrosis factor(TNF-a),nitric oxide(NO), interleukin-2,6(IL-2,IL-6) from 31 patients with virus myocarditis and 32 of healthy people were studied by radioimmunoassay and colorimetricochemical method,enzyme-linked immunossorbent assay.Results The serum levels of TNF-a,IL-2,IL-6,NO were remarkly higher than that of normal group, they had significant differenc...
Keywords:Tumor necrosis factor Nitric oxide Interleukin-2  Interleukin-6 Virus myocarditis  
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