| 强化胰岛素控制血糖对重度颅脑外伤患者的疗效及分析 |
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| 引用本文： | 梅涛,廖达光,贾若飞,徐立新,阙思伟,冯志君,冷海斌,王俊,陈华,陵姚,王年华.强化胰岛素控制血糖对重度颅脑外伤患者的疗效及分析[J].国际神经病学神经外科学杂志,2010,37(5). |
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| 作者姓名： | 梅涛 廖达光 贾若飞 徐立新 阙思伟 冯志君 冷海斌 王俊 陈华 陵姚 王年华 |
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| 作者单位： | 中南大学湘雅三医院神经外科;常德市第一人民医院神经外科; |
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| 摘 要： | 目的阐述强化胰岛素治疗控制血糖对NICU内重度颅脑外伤患者的感染率,NICU住院时间,神经功能预后及死亡率的影响。方法将202例入住NICU的重度颅脑外伤(TBI)患者前瞻性地随机分为两组,分别接受强化胰岛素治疗和传统的胰岛素治疗。结果随访6个月的总体死亡率,传统治疗组(Conventional Insulin Therapy,CIT)与强化治疗组(Intensive Insulin Therapy,IIT)相似(P=0.84)。接受CIT的患者感染率明显高于接受IIT组(P0.05)。接受IIT的患者在NICU的住院时间少于CIT组(P0.05)。研究期间的两组院内死亡率相似(P=0.90)。接受IIT的患者组随访6个月的GOS评分高于CIT组(P0.05)。结论强化胰岛素治疗能有效改善重症颅脑外伤患者预后。
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| 关 键 词： | 重度颅脑损伤 强化胰岛素 NICU 血糖 |
Control of blood glucose with intensive insulin therapy in patients with severe traumatic brain injury and the efficacy analysis |
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| Meitao,Liao Da-guang,Jiaruo-fei,Xuli-xin,Queshi-wei,Fengzhi-jun,Lenghai-bin,Wangju,Yaoling,Chenghua,Wanglian-hua.Control of blood glucose with intensive insulin therapy in patients with severe traumatic brain injury and the efficacy analysis[J].Journal of International Neurology and Neurosurgery,2010,37(5). |
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| Authors: | Meitao Liao Da-guang Jiaruo-fei Xuli-xin Queshi-wei Fengzhi-jun Lenghai-bin Wangju Yaoling Chenghua Wanglian-hua |
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| Affiliation: | Meitao1,2,Liao Da-guang1,Jiaruo-fei2,Xuli-xin2,Queshi-wei2,Fengzhi-jun2,Lenghai-bin2,Wangju2,Yaoling2,Chenghua2,Wanglian-hua2,1 Department of Neurosurgery,The 3rd Xiangya Hospital of Central South University,ChangSha 410006,China.2 Department of Neurosurgery,The First People's Hospital of Changde City,Changde,415000,China. |
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| Abstract: | Objective To compare intensive insulin therapy to conventional glucose control in patients with severe traumatic brain injury evaluating infection rate,days in NICU,in-hospital mortality and long-term neurological outcome.Methods Total of 202 Patients with severe TBI (GCS score 3-8) after admission were randomized to receive conventional insulin therapy or intensive insulin therapy.Results The in-hospital mortality and the 6-month mortality were similar in both groups.The infection rate in patients who rece... |
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| Keywords: | severe traumatic brain injury intensive insulin therapy NICU blood glucose |
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