前列腺增生合并前列腺炎患者前列腺液中尿酸浓度的研究

目的探讨前列腺液（EPS）中尿酸（uA）水平与前列腺增生（BPH）合并慢性前列腺炎（cP）的关系。方法收集准备行经尿道前列腺切除术（TURP）的患者280例，术前测定患者前列腺液中尿酸浓度及前列腺液中白细胞、前列腺结石情况，术后前列腺标本行病理检查，分为单纯增生组和增生合并前列腺炎组，将两组前列腺液和血液中尿酸浓度及两组合并前列腺结石数据进行统计学处理。结果BPH合并CP患者的EPS中uA水平与正常对照组比较差异有统计学意义（P〈0．05）。BPH合并CP患者前列腺结石检出率为71．9％．与对照组（40．4％）相比差异有统计学意义（P〈0．05）。结论EPS中UA水平可能与前列腺炎发病有关，合并慢性前列腺炎的前列腺增生患者前列腺结石发病率高于对照组，EPS中UA测定和前列腺结石的监测可能是诊断前列腺炎的有效指标。

Urea acid level of expressed prostatic secretion in benign prostate hyperplasia patients complicated with prostatitis

Objective To investigate the relationship between the inflammation of the prostate and the urea acid（UA） level of expressed prostatic secretion （EPS） in benign prostate hyperplasia patients, and to evaluate its clinical significance. Methods Two hundred and eighty patients with benign prostate hyperplasia（BPH） were divided into two groups by pathology： singlet BPH group（control group） and BPH complicated with inflammation group（ complic group）. We statistically analyzed the urea acld in EPS and blood,the prostate stones of the two groups. Results The UA level,the WBC number of EPS and the detection rate of prostatic calculus（71.9% ）in complic group were significantly higher than that in the control group（ P 〈 0.05）. Conclusions The UA level of EPS can cause the inflammtion of prostate and the rate of prostatic calculus is higher in complic group than that in control group, the determination of UA in EPS and the monitor of prostatic calculus maybe significant in diagnosis of prostatitis.