消痔灵注射结合外剥内扎术治疗混合痔的临床观察

目的观察消痔灵注射结合外剥内扎术治疗混合痔的临床疗效。方法将480例混合痔患者随机分为两组，治疗组360例，对照组120例，治疗组采用消痔灵注射结合外剥内扎术，对照组采用外剥内扎术，对比观察两组患者疗效，疼痛、创缘水肿、出血、肛门坠胀等常见并发症，痔核扎线脱落时间、创面愈合时间及复发率情况。结果治疗组和对照组总有效率，术后肛门坠胀，随访3个月、6个月和1年复发率，两组之间比较差异无统计学意义（P〉0．05）。治疗组和对照组术后疼痛积分、创缘水肿、出血等并发症，术后痔核扎线脱落时间，创面愈合时间，随访3年和5年复发率两组之间比较差异有统计学意义（P〈0．05）。结论消痔灵注射结合外剥内扎术治疗状混合痔优于传统的外剥内扎术。

Clinical Observation of Mixed Hemorrhoid Treated with Xiaozhiling Injec- tion and Milligan- Morgan Operation

Objective To observe the clinical efficacy on mixed hemorrhoid treated with xiaozhiling injection and Milligan - Morgan operation. Methods 480 cases of mixed hemorrhoid were randomized into two groups ,360 cases in a treatment group and 120 cases in a control group. In the treatment group, the combined therapy of xiaozhiling injection and Milligan - Morgan operation was adopted. In the control group, Mil- ligan - Morgan operation was applied. It was to compare and observe the efficacy, common complications such as pain, edema around the wound, bleeding and anal distension and bearing - down feeling, time of hemorrhoids defluvium,healing time as well as the recurrence rate for the patients between two groups. Results The differences were not significant statistically in the total effective rate, the postoperative anal distension and bearing- down feeling and the recurrence rate in the followup visit of 3 months,6 months and 1 year between the treatment group and the control group（ P 〉 0.05 ）. The differences were significant statistically in postoperative pain score, edema around the wound, bleeding, the time of postoperative hemorrhoids defluvium, healing time and the recurrence rate in the follow - up visit of 3 and 5 years between the treatment group and the control group（P 〈 0.05 ）. Conclusion The combined therapy of xiaozhiling injection and Milligan - Morgan operation is superior to Milligan - Morgan operation in the treatment of mixed hemorrhoid.