抗生素耐药性全球治理的发展历程及对中国的启示

目的:归纳总结抗生素耐药性全球治理的发展历程和每个阶段的特点,并为中国参与抗生素耐药性的全球治理提供启示。方法:采用范围综述的方法在ISI Web of Science、Pubmed、Medline等外文期刊数据库中搜索并筛选有关抗生素耐药性全球治理的相关文献,同时收集世界卫生组织、联合国、联合国粮农组织以及世界动物卫生组织等发布的相关资料。结果:抗生素耐药性全球治理的发展历程大致可分为三个阶段:以临床监测为主要策略、由发达国家主导的萌芽阶段;从卫生领域到卫生、农业、环境等多领域共同治理的快速发展阶段;多国家参与并且多领域共同治理的全面覆盖阶段。结论:全世界对于抗生素耐药性全球治理的关注度日益提升,我国应借鉴世界各国采取的有效行动,鼓励多领域协同治理抗生素耐药性问题,以更加积极主动的姿态参与全球治理,并逐步提高社会公众对抗生素耐药性的重视。

Policy evolution of China's antibiotic resistance governance and its enlightenment

Objective:This study examines China''s policy evolution of antibiotic resistance governance in different stages and provides enlightenment for further policy development.Methods:After systematically searching throughout information on policies and actions regarding antibiotic resistance governance on the websites of major ministries such as the National Health Commission,key information from these policies are extracted, and the policies and actionsare then summarized based on their issue timelines and key contents. Results:The governance of antibiotic resistance in China could be divided into three major stages:1) the drug control as the main governance strategy; 2) clinical surveillance and governance of antibiotic resistance, and 3) multi-disciplinary antibiotic resistance governance.Conclusions:To further address the antibiotic resistance governance,China should strengthen infection control and rational use of antibiotics within community,strengthen drug resistance management within the departments of agriculture and environment, in order to be more actively involved in the global actions in antibiotic resistance control,establish an inter-departmental and inter-disciplinary cooperation platform based on the "One Health" framework,and encourage the research and development of antibiotic alternative drugs.