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| 生存研究样本量设计表及其使用方法 | |
| 引用本文： | 赵国龙,孙爱民,魏金星,汲振余,陈洪涛,王月平,刘欣. 生存研究样本量设计表及其使用方法[J]. 河南医学研究, 2001, 10(4): 297-300 |
| 作者姓名： | 赵国龙 孙爱民 魏金星 汲振余 陈洪涛 王月平 刘欣 |
| 作者单位： | 1. 河南省医学科学研究所, 2. 郑州大学第一附属院, 3. 北京武警总队医院内科, |
| 摘 要： | 目的 :本文就两样本生存研究所需样本量用广义渐近正态法设计出 15 30个方案 ,制成设计表供临床使用。方法 :利用C语言编制程序 ,按通用格式打印设计表。结果 :常用方案查表可得。这些与两样本生存率检验相匹配 ,具有还原性 ,摆脱了比例危险的假设 ,在常见临床条件下观测功效符合预定功效。结论 :这些设计表适用于两样本癌症临床研究的设计 ,尤其便于临床医师或有关研究人员使用 |
| 关 键 词： | 渐近正态法 终检 试验设计 样本量 生存率 |
| 文章编号： | 1004-437X(2001)04-0297-04 |
| 修稿时间： | 2001-10-12 |
Design tables of the required sample sizes for survival studies and their appliocations |
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| ZHAO Guo long,SUN Ai min,WEI Jin xing,et al. Design tables of the required sample sizes for survival studies and their appliocations[J]. Henan Medical Research, 2001, 10(4): 297-300 | |
| Authors: | ZHAO Guo long SUN Ai min WEI Jin xing et al |
| Abstract: | Objective: Design tables of the required sample sizes for survival studies including 1,530 projects were made out based on the generalized asymptotic normal procedure for clinical applications. Methods: The procedure was programmed in the C language and the output was printed in the destgn tables with usual form. Results: Common projects can be found in the tables. They are matched with the test on two survival rates, reducible when there is no censoring, free from the assumption of proportional hazards, The observed power coinccides with the prescribed power in usual clinical situations. Conclusion: The tables are appropriate with planning clinical cancer studies, especially useful for clinicians or the relevant investigators. |
| Keywords: | asymptotic normal procedure censorship experimental design sample size survival rate |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
