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百令胶囊中甘露醇及腺苷含量测定方法的改进
引用本文:李全学,吴小红.百令胶囊中甘露醇及腺苷含量测定方法的改进[J].中国药师,2010,13(5):683-685.
作者姓名:李全学  吴小红
作者单位:1. 湖南中南科伦药业有限公司,湖南岳阳,414000
2. 岳阳市药品检验所
摘    要:目的:改进百令胶囊中甘露醇和腺苷的含量测定方法。方法:甘露醇的含量测定由醇提取改为水提取,腺苷的含量测定中改进流动相的组成及供试品溶液的制备方法。结果:改进后的含量测定方法能更准确地测定百令胶囊中甘露醇和腺苷的含量。结论:方法简便、易行,可用于百令胶囊的质量控制。

关 键 词:百令胶囊  甘露醇  腺苷  含量测定

Improvement of Determination Method of Mannitol and Adenosine in Bailing Capsules
Li Quanxue,Wu Xiaohong.Improvement of Determination Method of Mannitol and Adenosine in Bailing Capsules[J].China Pharmacist,2010,13(5):683-685.
Authors:Li Quanxue  Wu Xiaohong
Affiliation:1. Hunan Zhongnan Kelun Pharmaceutical Co. , Ltd. , Hunan Yueyang 414000, China; 2. Yueyang Institute for Drug Control)
Abstract:Objective: To improve the determination method of mannitol and adenosine in Bailing Capsules. Method: The content determination method of mannitol was changed from extract with ethanol to extract with water, and the content determination method of adenosine, the mobile phase and preparation of sample solution was improved. Result: The improved method could he used for determi- nation the contents of mannitol and adenosine accurately. Conclusion: The method is simple. It can be used for quality control of Bailing Capsules.
Keywords:Bailing Capsules  Mannitol  Adenosine  Content Determination
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