激素性股骨头缺血坏死病理机制的研究进展

股骨头缺血坏死是骨科中较为常见的疾病,其最主要的病因是长期或过量使用激素,由此,医学领域对激素性股骨头缺血坏死的病发机制进行了实验与研究。现阶段出现的有关激素性股骨头缺血坏死的病理研究,主要包括诱导性细胞凋亡学说、诱导性骨质疏松学说及血黏度提升学说等。该研究主要对激素性股骨头缺血坏死相关病理机制进行研究综述。

The Research Progress of Sex Hormone Ischemic Necrosis of Femoral Head

Ischemic necrosis of femoral head was more common in the orthopaedic disease, its main cause was long-term or ex- cessive use of glucocorticoid, as a result, the mechanisms of glucocorticoid on ischemic necrosis of the femoral head has been car- ried on the experiment and research. At this stage, pathological study of the glucocorticoid on ischemic necrosis of the femoral head, were mainly includes the theory of induced apoptosis, induced osteoporosis theory and the theory of blood viscosity increase, etc., This article had been reviewed by pathological mechanism of glucocorticoid-induced ischemic necrosis of femoral head.