| sICAM-1、U-ALB在妊娠期高血压疾病早期肾损伤中的变化及相关性研究 |
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| 引用本文： | 张燕,刘爱敏,蒋玉红,山洁,于春波.sICAM-1、U-ALB在妊娠期高血压疾病早期肾损伤中的变化及相关性研究[J].中国优生与遗传杂志,2011(5):60-61. |
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| 作者姓名： | 张燕 刘爱敏 蒋玉红 山洁 于春波 |
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| 作者单位： | 青岛市海慈医疗集团;青岛市妇女儿童医疗保健中心; |
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| 摘 要： | 目的探讨妊娠期高血压疾病早期肾损伤中尿微量白蛋白(U-ALB)与可溶性细胞间粘附因子-1水平变化及相关性分析。方法测定正常妊娠组、妊娠期高血压组U-ALB含量;测定正常未孕组、正常妊娠组、妊娠期高血压组、子痫前期组4组(孕32-35周)sIACM-1值;所测值进行组间比较并对sIACM-1、U-ALB进行相关性分析。结果妊娠期高血压患者U-ALB阳性率(60.00%)明显高于正常妊娠组(10.00%),P<0.01;sIACM-1正常妊娠组高于未孕组,P<0.05;与正常妊娠组比较,妊娠期高血压组高于正常妊娠组,P<0.05;子痫前期组明显高于正常妊娠组,P<0.01;与妊娠高血压组比较P<0.05。妊娠期高血压组sIACM-1与U-ALB相关性分析,相关系数(r)为0.723;P值<0.01。结论 U-ALB、sIACM-1在妊娠期高血压疾病早期肾损伤中含量明显增高,两者之间呈正相关。
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| 关 键 词： | 妊娠期高血压 细胞间粘附因子-1 尿微量白蛋白 |
The study of changes and correlation betwee sICAM-1,U-ALB in pregnancy induced hypertension with early renal injury |
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| ZHANG Yan,LIU Ai-min,JIANG Yu-hong,SHAN Jie,YU Chun-bo..The study of changes and correlation betwee sICAM-1,U-ALB in pregnancy induced hypertension with early renal injury[J].Chinese Journal of Birth Health & Heredity,2011(5):60-61. |
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| Authors: | ZHANG Yan LIU Ai-min JIANG Yu-hong SHAN Jie YU Chun-bo |
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| Affiliation: | ZHANG Yan,LIU Ai-min,JIANG Yu-hong,SHAN Jie,YU Chun-bo.(1.Medical Group Qingdao HaiCi,2.Qingdao Center for Women and Children Health Care) |
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| Abstract: | Objective: To investigate the early renal injury in hypertensive disorders in pregnancy in the urine albumin(U-ALB) and soluble intercellular adhesion molecule-1 levels and correlation analysis.Methods: Determined the normal pregnancy group,gestational hypertension group U-ALB levels;determination of the normal nonpregnant group,normal pregnancy,gestational hypertension,preeclampsia group 4(32-35 weeks gestation) sIACM-1 value;The measured value of the comparison between groups and sIACM-1,U-ALB correlation... |
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| Keywords: | Gestational hypertension Intercellular adhesion molecule-1 Urinary albumin |
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