川麦冬药材中二氧化硫来源及残留积累动态分析

目的:分析川麦冬药材中SO_2来源及残留量积累动态变化,为解决其SO_2残留超标问题提供理论依据。方法:收集主产区不同方法加工的川麦冬药材28份,测定SO_2残留量,根据测定结果对煤炭火烘烤和熏硫2种加工方法在加工过程中川麦冬药材SO_2残留积累动态进行考察。结果:产地收集的28份样品中SO_2残留量超标率35.71%,SO_2来源为煤炭火烘烤和硫磺熏蒸。SO_2残留量和烘烤时间成正比,超标临界时间在8~10 h;SO_2残留量和硫磺熏蒸时间、药材水分含量均呈正比关系,鲜麦冬熏硫1 h后SO_2残留量可高到1 017.69 mg·kg~(-1)。结论:从麦冬药材质量和安全用药考虑,在麦冬产地加工过程中应当禁止熏硫并严格控制煤炭火烘烤时间。

Sources and Residue Accumulation Dynamic Analysis of Sulfur Dioxide in Ophiopogonis Radix

Objective: To analyze sources and residue accumulation dynamic change of SO₂ in Ophiopogonis Radix for providing a theoretical basis to solute problem that SO₂ residue in Ophiopogonis Radix exceeded the standard. Method: Twenty-eight medicinal materials of Ophiopogonis Radix were collected, which were processed with different methods in main producing area of Sichuan.Residue of SO₂ in samples were measured.Based on measurement results and after processed by coal fire baking and smouldering sulphur, residue accumulation dynamic change of SO₂ in Ophiopogonis Radix were investigated. Result: Residue of SO₂ in 28 samples exceeded the standard with rate of 35.71%.Sources of SO₂ residue were coal fire baking and smouldering sulphur.SO₂ residue was in direct proportional to baking time.Marginal time of SO₂ residue out of the limit was 8-10 h.SO₂ residue was also in direct proportional to smoked sulfur time and material moisture content.SO₂ residue reached up to 1 017.69 mg·kg^-1 when fresh Ophiopogonis Radix was processed with smouldering sulphur for only 1 h. Conclusion: Consider of quality and medicine safety of Ophiopogonis Radix, it should be forbidden with smouldering sulphur and control baking time strictly in processing of Ophiopogonis Radix.