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Effect of Various Electrolytes on the Phase Separation and Thermodynamic Properties of p-Tert-Alkylphenoxy Poly (Oxyethylene) Ether in the Absence/Presence of Drugs
Authors:Muhammad Akhlaqur Rahman Khan  Md Ruhul Amin  Shamim Mahbub  Md Masud Alam  Malik Abdul Rub  Md Anamul Hoque  Mohammed Abdullah Khan  Abdullah M Asiri
Affiliation:1. Department of Chemistry, Jahangirnagar University, Savar, Dhaka, 1342, Bangladesh;2. Department of Chemistry, Mawlana Bhashani Science and Technology University, Santosh, Tangail, 1902, Bangladesh;3. Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah, 21589, Saudi Arabia

Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, 21589, Saudi Arabia

Abstract:Cloud point (CP) measurements of 4-(1,1,3,3-tetramethylbutyl) phenyl-polyethyleneglycol (Triton X-100 (TX-100)) were performed in aqueous solution in the presence of drug Amikacin sulfate (AS)/Neomycin sulfate (NS)/(AS/NS+ different inorganic salts). In aqueous solution, the CP values of TX-100 first decrease with increasing concentration and then increase with increasing surfactant concentration. The CP values of TX-100 solutions were found to increase with the increasing concentration of the AS/NS drug. The CP values of TX-100-AS/NS mixtures were also observed to decrease with the increase of the concentration of salt. Different thermodynamic parameters such as standard free energy (urn:x-wiley:10973958:media:jsde12248:jsde12248-math-0001), standard enthalpy (urn:x-wiley:10973958:media:jsde12248:jsde12248-math-0002) as well as the standard entropy (urn:x-wiley:10973958:media:jsde12248:jsde12248-math-0003) change of phase separation were calculated and discussed in relation to molecular interactions.
Keywords:Cloud point  TX-100  Amikacin sulfate  Electrolyte  Neomycin sulfate  Thermodynamic parameters
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