Affiliation: | 1. Department of Chemistry, Jahangirnagar University, Savar, Dhaka, 1342, Bangladesh;2. Department of Chemistry, Mawlana Bhashani Science and Technology University, Santosh, Tangail, 1902, Bangladesh;3. Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah, 21589, Saudi Arabia
Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, 21589, Saudi Arabia |
Abstract: | Cloud point (CP) measurements of 4-(1,1,3,3-tetramethylbutyl) phenyl-polyethyleneglycol (Triton X-100 (TX-100)) were performed in aqueous solution in the presence of drug Amikacin sulfate (AS)/Neomycin sulfate (NS)/(AS/NS+ different inorganic salts). In aqueous solution, the CP values of TX-100 first decrease with increasing concentration and then increase with increasing surfactant concentration. The CP values of TX-100 solutions were found to increase with the increasing concentration of the AS/NS drug. The CP values of TX-100-AS/NS mixtures were also observed to decrease with the increase of the concentration of salt. Different thermodynamic parameters such as standard free energy ( ), standard enthalpy ( ) as well as the standard entropy ( ) change of phase separation were calculated and discussed in relation to molecular interactions. |