| 莫西沙星相关横纹肌溶解症2例 |
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| 引用本文： | 任晓蕾,徐攀,李玉珍.莫西沙星相关横纹肌溶解症2例[J].药物不良反应杂志,2010,12(3):217-218. |
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| 作者姓名： | 任晓蕾 徐攀 李玉珍 |
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| 作者单位： | 北京大学人民医院药剂科,北京,100044 |
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| 摘 要： | 2例男性患者,年龄分别为87岁和74岁,均因肺部感染给予莫西沙星0.4g,1次/d静脉滴注。第3天均出现CK升高及尿潜血阳性。CK分别为5964U/L和3531U/L。且例1出现双侧腓肠肌压痛。停用莫西沙星,2例患者分别给予头孢他啶及美罗培南,并行碱化尿液治疗,症状逐渐好转。
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| 关 键 词： | 莫西沙星 不良反应 横纹肌溶解症 |
Rhabdomyolysis related to moxifloxacin in two patients |
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| Ren Xiaolei,Xu Pan,Li Yuzhen.Rhabdomyolysis related to moxifloxacin in two patients[J].Adverse Drug Reactions Journal,2010,12(3):217-218. |
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| Authors: | Ren Xiaolei Xu Pan Li Yuzhen |
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| Affiliation: | ( Department of Pharmacy,People’s Hospital,Peking University,Beijing 100044,China) |
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| Abstract: | Two male patients,aged 87 and 74 years,respectively,received an IV infusion of moxifloxacin 0. 4 g once daily for pulmonary infections. On day 3,they both developed creatine kinase elevation and positive occult blood in urine. Their CK levels were 5 964U/L and 3 531U/L,respectively. Patient 1 experienced pressing pain on bilateral calf muscle. Moxifloxacin was discontinued and the two patients were given ceftazidime and meropenem,respectively. Treatment with alkalinization of their urine was given and their symptoms improved. |
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| Keywords: | moxifloxacin adverse reactions rhabdomyolysis |
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