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岗梅根化学成分的研究
引用本文:蔡艳,张庆文,李旨君,范春林,王磊,张晓琦,叶文才.岗梅根化学成分的研究[J].中草药,2010,41(9):1426-1429.
作者姓名:蔡艳  张庆文  李旨君  范春林  王磊  张晓琦  叶文才
作者单位:暨南大学药学院中药及天然药物研究所,广东 广州 510632;暨南大学 中药药效物质基础及创新药物研究广东省高校重点实验室,广东 广州 510632;澳门大学中华医药研究院,澳门;暨南大学药学院中药及天然药物研究所,广东 广州 510632;暨南大学药学院中药及天然药物研究所,广东 广州 510632;暨南大学 中药药效物质基础及创新药物研究广东省高校重点实验室,广东 广州 510632;暨南大学药学院中药及天然药物研究所,广东 广州 510632;暨南大学 中药药效物质基础及创新药物研究广东省高校重点实验室,广东 广州 510633
基金项目:广东省自然科学基金团队项目,澳门特别行政区科学技术发展基金,广东省科技计划国际合作项目
摘    要:目的研究岗梅Ilexasprella根的化学成分。方法采用硅胶、凝胶和RP-HPLC等色谱方法对岗梅根的化学成分进行分离纯化,并根据理化性质和波谱数据鉴定化合物的结构。结果从岗梅根的70%乙醇提取物中分离得到10个三萜及其皂苷类化合物,分别鉴定为28-O-β-D-glucopyranosyl pomolic acid(1)、冬青苷XXIX(ilexo-side XXIX,2)、冬青苷B(ilexoside B,3)、刺参苷F(monepaloside F,4)、长圆冬青苷B(oblonganoside B,5)、3-O-β-D-xylopyranosyl-3β-hydroxyurs-12,18(19)-dien-28-oic acid 28-β-D-glucopyranosyl ester(6)、毛冬青皂苷B(ilexsapo-nin B,7)、randialic acid B(8)、毛冬青酸(ilexolic acid,9)和19-去氢乌索酸(19-dehydroursolic acid,10)。结论化合物1~9均为首次从该植物中分离得到。

关 键 词:岗梅根  三萜  三萜皂苷
收稿时间:2010/2/20 0:00:00

Chemical constituents from roots of Ilex asprella
CAI Yan,ZHANG Qing-wen,LI Zhi-jun,FAN Chun-lin,WANG Lei,ZHANG Xiao-qi and YE Wen-cai.Chemical constituents from roots of Ilex asprella[J].Chinese Traditional and Herbal Drugs,2010,41(9):1426-1429.
Authors:CAI Yan  ZHANG Qing-wen  LI Zhi-jun  FAN Chun-lin  WANG Lei  ZHANG Xiao-qi and YE Wen-cai
Affiliation:Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China;Instituet of Chinese Medical Sciences, University of Macau, Macau, China;Instituet of Chinese Medical Sciences, University of Macau, Macau, China;Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China;Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Guangzhou 510632, China;Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Guangzhou 510632, China;Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Guangzhou 510632, China;Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Guangzhou 510632, China
Abstract:
Keywords:Ilex asprella(Hook  et Arn  ) Champ  ex Benth    triterpenes  triterpenoid saponins
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