基于中医要素分析以及源于精气理论运用肺岩宁方治疗肺癌

目的:探讨肺癌的中医症候要素分布与临床相关因素的关系以及源于精气理论的肺岩宁方对中医要素的影响。方法:选取2016年11月至2017年11月潍坊市中医院肿收治的肺癌患者118例作为研究对象。采用临床病理学调查方法对118例对象进行阴虚要素、阳虚要素、气虚要素、血虚要素及无虚症要素5种要素类型分型分析,分别应用单因素方差分析、秩和检验、卡方检验分析各要素与年龄、性别、病程、ECOG评分、治疗方法、病理类型及肿瘤位置的关系,并观察肺岩宁方对各中医要素的影响。结果:肺癌的中医要素以阴虚及气虚要素为主,占总要素的94. 07%;阳虚要素与放疗、手术有关(P <0. 05);血虚要素与病程、ECOG评分、手术有关(P <0. 05);气虚要素与ECOG评分有关(P <0. 05);肺岩宁方对阴虚及气虚要素改善明显(P <0. 05)。结论:阴虚要素及气虚要素在肺癌的中医要素分布上占主导地位,具有显著性;肺岩宁方对改善精气两亏型肺癌患者的症状及生命质量上有显著的疗效,具有重要的应用价值。

Analysis Based on Syndrome Factors of Traditional Chinese Medicine and Application of Feiyanning Decoction Originated from Jingqi Theory on Lung Cancer

To investigate the relationship between the distribution of traditional Chinese medicine (TCM) syndrome factors and clinical factors in lung cancer, and the influence of Feiyanning Decoction originated from Jingqi theory on TCM factors.Methods:A total of 118 patients were recruited from Weifang Hospital of Traditional Chinese Medicine from November 2016 to November 2017.The clinical pathological investigation method was used to classify and analyze the five elements of yin deficiency, yang deficiency, qi deficiency, blood deficiency and no deficiency in 118 cases.The relationship between each factor and age, sex, course of disease, ECOG score, treatment method, pathological type and location of tumors was analyzed by single factor analysis of variance, rank sum test and chi square test respectively.The effects of Feiyanning Decoction on the TCM elements was analyzed.Results:The main factors of TCM in lung cancer were yin deficiency and qi deficiency, accounting for 94.07% of the total factors; yang deficiency factor was related to radiotherapy and operation (P<0.05); blood deficiency factor was related to the course of disease, ECOG score, and operation (P<0.05); qi deficiency factor was related to the ECOG score (P<0.05); Feiyanning Decoction significantly improved yin deficiency and qi deficiency (P<0.05).Conclusion:Yin deficiency factor and qi deficiency factor play a leading role in the distribution of TCM elements in lung cancer.Feiyanning Decoction has significant curative effects on improving the symptoms and quality of life of patients with deficiency of essence and qi, which is worthy of clinical promotion.