应用实时三维超声心动图定量评价心肌梗死后左室节段收缩功能及同步性

目的:探讨实时三维超声心动图(RT-3DE)定量评价陈旧性心肌梗死患者左心室受累节段的收缩功能及收缩同步性的临床应用价值。方法:32例陈旧性心肌梗死患者(心梗组)和20例健康者(正常组)行实时三维超声心动图检查,3D QLAB软件对三维数据库行定量分析,检测左室各节段射血分数(REF)及同步性参数即左室16节段、12节段(6个基底段和6个中间段)、6个基底段达收缩末最小容积的时间标准差以及时间最大差值,经心动周期标化后为Tmsv16-SD%、Tmsv12-SD%、Tmsv6-SD%、Tmsv16-Dif%、Tmsv12-Dif%和Tmsv6-Dif%。结果:与正常组相应节段对照,心梗组受累节段REF显著降低,TmsvSD-16%、Tmsv-16Dif%显著增加。结论:RT-3DE可客观定量的评价心肌梗死节段的收缩功能及收缩同步性。

Quantitative evaluation of regional left ventricular systolic function and synchrony in patients with myocardial infarction using real-time three-dimensional echocardiography

Objective: To assess the clinical value of real-time three-dimensional echocardiography(RT-3DE) in evaluating regional left ventricular systolic function and synchrony in patients with old myocardial infarction(OMI).Methods: RT-3DE was performed on 32 patients with OMI(the myocardial infarction group) and 20 normal subjects(the control group).The three-dimensional image data was analyzed with QLAB software.The regional ejection fraction(REF),the difference(Dif) and standard deviation(SD) of the time to minimal systolic volume(Tmsv) in 16,12 and 6 segments were obtained and normalized by R-R interval(TmsvSD% and TmsvDif%).Results: Compared with the normal segments in control group,the REF of the myocardial infarction segments decreased significantly,while Tmsv16-SD% and Tmsv16-Dif% increased.Conclusion: RT-3DE can objectively evaluate regional left ventricular systolic function and synchrony in patients with myocardial infarction.