Effect of the dipeptide vilon on activity of digestive enzyme in rats of various ages |
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| Authors: | Khavinson V K Timofeeva N M Malinin V V Egorova V V Nikitina A A |
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| Affiliation: | (1) Northwestern Division of the Russian Academy of Medical Sciences, St. Petersburg Institute of Bioregulation and Gerontology, Russia;(2) I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg |
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| Abstract: | Peroral administration of Vilon (Lys-Glu) to male and female Wistar rats aging 3 and 11 months changed activity of digestive enzymes (invertase, maltase, alkaline phosphatase, and amino- and dipeptidases) in various portions of the gastrointestinal tract. The increase in enzyme activity was most pronounced in 11-month-old animals, which diminished differences between rats of various ages. Our results indicate that Vilon produces positive effects on digestive enzyme activity during aging. |
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| Keywords: | aging Vilon peptides digestive enzymes gastrointestinal tract |
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