观察卵磷脂络合碘片(沃丽汀)治疗黄斑水肿的临床疗效

目的：〖HTSS〗观察卵磷脂络合碘片治疗黄斑水肿的临床疗效。方法：〖HTSS〗选择2014年2月至2015年2月于我院治疗的66例（66眼）黄斑水肿患者，随机分为观察组（n=33）、和对照组（n=33）。两组患者均行雷珠单抗联合激光光凝治疗，观察组在此基础上加用磷脂络合碘片，观察两组患者在治疗前后最佳矫正视力（LogMAR BVCA）及黄斑中心凹厚度（CMT）的变化，以及治疗6个月后两组患者的临床疗效。结果：与治疗前相比，两组患者治疗后1、2、3、6月的LogMAR BVCA和CMT平均值均显著降低（P< 005）。观察组在治疗后2、3、6月的LogMAR BVCA和CMT平均值均显著低于对照组（P< 005）。治疗6个月后，观察组的总有效率为970%，对照组的总有效率为818%，两组相比差异具有统计学意义（P< 005）。结论：采用卵磷脂络合碘片辅助雷珠单抗联合激光光凝治疗黄斑水肿有利于改善患者视力、促进水肿消退，并且巩固疗效，值得在临床中推广应用。

Study on efficacy of iodized lecithin tablets in treatment of macular edema

  Objective:〖WT5”BZ〗To explore the efficacy of iodized lecithin in treatment of macular edema.Methods: 〖WTBZ〗From February 2014 to February 2015,a total of 66 patients(66 eyes) with macular edema in our hospital were divided into control group(n=33) and observation group(n=33) randomlyIodized lecithin combined with conventional therapy was applied in observation group,and conventional therapy was applied in control groupObserved the change of best corrected visual acuity(LogMAR BVCA) and central macular thickness(CMT) in the two groups pre and post treatment,and observation on clinical curative effect of the two groups at 6 month after treatment.Results: Compared with pre treatment,the average value of LogMAR BVCA and CMT in the two groups showed significantly decreased at 1,2,3,6 months after therapy(P< 005)Compared with control group,the observation group could significantly decrease the average value of LogMAR BVCA and CMT at 2,3,6 months after therapy (P< 005)After 6 months of treatment,the total effective rate of observation group showed significantly higher than control group (P< 005).Conclusion: 〖WTBZ〗Iodized lecithin combined with conventional therapy have a significant curative effect to improve vision,promote regression of macular edema,and enhance the treatment effectIt′s worthy of clinic application.