肝癌三维适形放疗设野方法的研究

目的：探讨肝癌三维适形放射治疗照射野的设计方法。方法：利用上海拓能（Topslane）公司的三维治疗计划系统对112例肝癌患者，根据医生要求的CTV和周围的敏感器官限制受量，进行三维适形放射治疗计划设计，结合剂量曲线分布情况和剂量体积直方图（DVH）选择最佳治疗方案。结果：以肿瘤中心点为剂量归一点，80％～90％的剂量线均能包绕靶区体积，而周围正常组织受量都在理想的范围内。结论：对肝癌的三维治疗计划设计时，要根据病人不同的病变部位采取不同的设野方法，这样能使靶区剂量分布均匀，适形度好，同时也有效地保护了敏感器官，从而提高肿瘤剂量及肿瘤局部控制率。

A study of field designing methods in 3 - dimensional conformal radiation therapy for liver cancer

Objective ：To observe the field designing methods in 3 -dimensional conformal radiation therapy （3D -CRT） for liver cancer. Methods. According to the limits of the CTV and neighbor sensitive organs＇absorbed dose to make 3D - CRT plans for 112 liver cancer patients by using Topslaneg 3 - dimensional therapy plan system（ TPS）, and optimize the therapy scheme base on the dose curves and the dose -volume histogram（DVH）. Results： To take the tumor＇s center as the dose unitary point, target region was surrounded by 80% -90% dose lines and the normal organs＇absorbed dose was in desirable range. Conclusion： To plan a 3D -CRT for the liver cancer shonld adopt ap- propriate field design methods according to patients＇pathological changes position sensitive organs can be protected effectively, so can improve the tumorg absorbed dose and local control rate.