泌尿生殖道支原体感染及耐药性分析

目的探讨2008~2009年泌尿生殖道支原体感染药敏情况。方法应用珠海市浪峰生物技术研究所提供的试剂盒,对2008~2009年皮肤科和妇科门诊就诊患者共1 024例进行支原体培养鉴定及药敏试验。结果支原体总感染率为53.32%,其中解脲支原体(Uu)、人型支原体(Mh)+Uu、Mh的感染率分别为41.80%、9.96%、1.56%。男、女感染率分别为21.45%和65.85%,女性感染率明显高于男性,差异有统计学意义(P<0.05)。药敏试验结果表明,Uu、Mh+Uu、Mh感染对12种抗菌药物的耐药率各不相同,但对交沙霉素、强力霉素、美满霉素耐药率均较低。结论柳州地区泌尿生殖道支原体感染以Uu单独感染为主,感染情况有性别差异。临床治疗前应尽可能进行支原体培养及药敏试验,以合理规范用药,防止耐药菌株的产生。

Analysis of mycoplasma infection in urogenital tract and its drug resistance

Objective To explore the mycoplasma infection in urogenital tract and its drug sensitivity during 2008-2009. Methods We applied Zhuhai city crest biotechnology institutef s kit for mycoplasma identification and susceptibility testing of dermatology and gynecology clinic patients in 1 024 cases from 2008 to 2009. Results The total infection rate of mycoplasma was 53. 32%, the infection rates of Uu, Mh＋k Uu, Mh were 41. 8%,9. 96%, 1.56% respectively. Infection rates in male and female were 21.45% and 65.85% respectively, the infection rate of women＇s was significantly higher than that of the male＇s, the difference was significantly different（P〈0.05）. The drug sensitivity test results showed as followed, the resistance rates of Uu, Mh ＋ Uu, Mh infection on 12 types of an tibiotics were different,but all the drugs resistance to josamycin,doxycycline,minocycline were low. Conclusion The main infection of mycoplasma in this area was Uu infection,but the infection status was different. So we should culture mycoplasma and do the drug sensitivity test before clinical treatment, for the rational use of medicine and preventing the emergence of resistant strains.