|
|||||
|
|
| 兰州地区女性感染HPV及其基因类型分析 | |
| 引用本文： | 杨燕,刘会玲,虎镯,高飞艳,杨毓琴.兰州地区女性感染HPV及其基因类型分析[J].现代生物医学进展,2011,11(21):4069-4071. |
| 作者姓名： | 杨燕 刘会玲 虎镯 高飞艳 杨毓琴 |
| 作者单位： | 1. 兰州大学第一临床医学院 甘肃兰州730000 2. 甘肃省人民医院妇产科 甘肃兰州730000 3. 甘肃省中医学院 甘肃兰州730000 4. 兰州大学病原生物学研究所 甘肃兰州730000 |
| 摘 要： | 目的:了解兰州地区成年女性感染人乳头瘤病毒(humanpapillomavirus,HPV)及其基因类型分布状况,为本地区HPV分子流行病学研究提供理论依据。方法:利用PCR技术分别对100例妇科门诊就诊者进行HPV基因亚型检测。结果:100例样品中,HPV DNA检出率为19%(19/100),其中HPV16 DNA感染率15%(15/100),HPV58 DNA感染率3%(3/100),HPV18 DNA感染率2%(2/100),HPV 16与HPV18双重感染1例。结论:本地区成年女性HPV感染主要以HPV16多见,而HPV16与恶性肿瘤密切相关,因此对HPVDNA阳性者定期随访,有利于宫颈癌的防治。 |
| 关 键 词： | 人乳头瘤病毒(HPV) 分型 PCR |
Study on the Human Papillomavirus (HPV) Infection and Genotypes Distribution Pattern ofWomen in Lanzhou Area |
|
| YANG Yan,LIU Hui-ling,HU Zhuo,GAO Fei-yan,YANG Yu-qing.Study on the Human Papillomavirus (HPV) Infection and Genotypes Distribution Pattern ofWomen in Lanzhou Area[J].Progress in Modern Biomedicine,2011,11(21):4069-4071. | |
| Authors: | YANG Yan LIU Hui-ling HU Zhuo GAO Fei-yan YANG Yu-qing |
| Affiliation: | g2△(1 First Clinical Medical College of Lanzhou University,Gansu,Lanzhou 730000;2 People’s Hospital of Gansu Province,Gansu,Lanzhou 730000;3 Gansu College of Traditional Chinese Medicine,Gansu,Lanzhou 730000;4 Institute of Pathogenic Biology of Lanzhou University,Gansu,Lanzhou 730000) |
| Abstract: | Objective: This is an epidemiological study on the distribution pattern of HPV genolypes in Lanzhou area.Methods: One hundred samples were detected for HPV genotyping by using PCR technique.Results: In 100 samples,the positive rate of HPV DNA was 19%.HPV16 DNA was 15 %(15/100).HPV58 DNA was 3%(3/100) and HPV18 DNA was 2 %(2/100).And one case infect-ed both HPV16 and HPV18.Conclusion: The most prevalent HPV genotypes in Lanzhou area were HPV 16 which is closely related with the malignancy.Therefore peoples w... |
| Keywords: | Human papillomavirus(HPV) Genotyping PCR |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |
| 点击此处可从《现代生物医学进展》浏览原始摘要信息 | |
| 点击此处可从《现代生物医学进展》下载全文 | |
