Abstract: | One-hundred and fifteen subjects were diagnosed with Helicobacter pylori (HP) infection and 93 subjects with ?atrophic gastritis (AG) from tests of HP antibodies or serum levels of pepsinogen I and pepsinogen II involving 210 ?inhabitants, who participated in the health check-up program. Logistic regression analysis found that refreshing ?(isotonic) beverages significantly reduced the risk of HP infection (odds ratio: 0.767, 95%C.I.: 0.616-0.956). A higher ?frequency of intake for margarine (odds ratio: 1.413, 95%C.I.: 1.080-1.848), cheese (odds ratio: 1.416, 95%C.I.: ?1.044-1.920), Tsukemono (odds ratio: 1.277, 95%C.I.: 1.000-1.631) or Cola-beverages (odds ratio: 1.471, 95%C.I.: ?1.051-1.239) showed a significantly increased risk of AG. In addition, high serum values of â-carotene (odds ratio: ?0.691, 95%C.I.: 0.498-0.958), linoleic acid (odds ratio: 0.594, 95%C.I.: 0.382-0.924), and ã-linolenic acid (odds: 0.987, ?95%C.I.: 0.976-0.998) were found to reduce the risk of AG, but not HP infection. Furthermore, these results suggest ?that a more frequent intake of margarine, Tsukemono (pickled vegetables), or Cola-beverages may be a risk factor ?for AG, while foods rich in carotenes, such as, â-carotene and n-6PUFAs, such as ã-linolenic acid, may reduce the ?risk of AG. |