我国心脏死亡器官捐献供肝现状及其肝移植的临床进展

肝移植是治疗终末期肝病的重要手段,但是供体短缺的问题日益显现,因此适合我国国情,同时符合国际标准的心脏死亡器官捐献(DCD)应该是现阶段缓解器官短缺的一种重要手段。本文回顾了国际上DCD肝移植的曲折发展历程,通过对DCD肝移植的定义与分类、伦理原则、适应证、获取方案、捐献情况和临床效果进行综述,认为DCD供肝是目前我国肝移植供体极度短缺大环境下的一支"生力军"。随着其工作的深入开展,必将成为我国肝移植的重要组成部分。

Clinical progress in donation after cardiac death liver transplantation in China

Liver transplantation is an important treatment for end - stage liver disease, but donor shortage is becoming increasingly apparent, so donation after cardiac death （DCD） , which is suitable for the national conditions of China and consistent with international standards, is an important measure for easing the organ shortage at the present stage. The tortuous development process of international DCD liver trans- plantation, including the definition and classification, ethical principles, indications, acquisition program, donation cases, and clinical re- suits, is reviewed. It is considered that DCD donor liver is a solution to current donor shortage in liver transplantation in China. With the development of DCD liver transplantation, it will become an important part of liver transplantation in China.