| 阻塞性睡眠呼吸暂停低通气综合征与醒后卒中之间关系的研究进展 |
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| 引用本文： | 傅翔,李洁,刘昱璐,吴嘉靖,刘春风.阻塞性睡眠呼吸暂停低通气综合征与醒后卒中之间关系的研究进展[J].中国卒中杂志,2019,14(4):352-356. |
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| 作者姓名： | 傅翔 李洁 刘昱璐 吴嘉靖 刘春风 |
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| 作者单位： | 1215004 苏州大学附属第二医院神经内科2苏州市神经疾病临床中心 |
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| 基金项目： | 苏州市科技发展计划－产业技术创新专项（民生科技－医疗卫生应用基础研究）项目（SYSD2016096）
苏州市临床医学中心项目（Szzx201503）
江苏省医学重点学科（ZDXKB2016022）
苏州市科技计划项目（SYS201624） |
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| 摘 要： | 醒后卒中(wake-up stroke,WUS)患者通常由于发病时间不确切而延误包括静脉溶栓在内的超早期治疗,并且WUS与清醒时发病的缺血性卒中相比在危险因素及发病机制等方面尚存在差异。因此,了解WUS的危险因素并且早期干预具有重要意义。目前,关于WUS危险因素的研究表明OSAHS是WUS的重要危险因素之一,但是OSAHS引起WUS的机制尚未阐明。本文就目前OSAHS与WUS之间关系的研究进展进行综述。
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| 关 键 词： | 醒后卒中 阻塞性睡眠呼吸暂停低通气综合征 缺血性卒中 |
| 收稿时间： | 2018-11-17 |
Advance in Correlation of Obstructive Sleep Apnea Hypopnea Syndrome and Wake-up Stroke |
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| FU Xiang,LI Jie,LIU Yu-Lu,WU Jia-Jing,LIU Chun-Feng.Advance in Correlation of Obstructive Sleep Apnea Hypopnea Syndrome and Wake-up Stroke[J].Chinese Journal of Stroke,2019,14(4):352-356. |
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| Authors: | FU Xiang LI Jie LIU Yu-Lu WU Jia-Jing LIU Chun-Feng |
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| Affiliation: | (The Second Affiliated Hospital of Soochow University,Suzhou 215000,China;Suzhou Clinical Research Center for Neurological Diseases,Suzhou 215000,China) |
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| Abstract: | Due to the uncertain onset time, wake-up stroke (WUS) patients are usually excluded
from thrombolytic therapy. There were still some differences in risk factors and pathogenesis
between WUS and stroke occurring while awake. It's important to investigate the related risk factors
and give timely intervention for WUS. Now many studies confirmed that OSAHS was one of the
important risk factors of WUS, while the mechanism of OSAHS causing WUS is still unclear. This
article reviewed the advance in the relationship between OSAHS and WUS. |
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| Keywords: | Wake-up stroke Obstructive sleep apnea hypopnea syndrome Ischemic stroke |
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