经皮椎体成形术治疗骨质疏松性椎体骨折

目的观察经皮椎体成形术（PVP）治疗骨质疏松性椎体压缩性骨折的初步临床疗效。方法自2003年2月至2005年12月，使用强生公司PMMA（聚甲基丙烯酸甲酯）作为充填材料，在C臂X线机（以下简称C臂）透视监视下，经皮单侧或双侧椎弓根穿刺行椎体成形术41例共45个骨质疏松性胸、腰椎压缩性骨折的椎体。结果成功率100％。PMMA在胸椎平均充填4ml，腰椎平均充填5ml，术中PMMA渗漏7例，但无1例发生严重并发症。随访3～12个月，完全缓解（CR）、部分缓解（PR）、轻微缓解（MR）和无效（NR）分别为56．1％，39．O％，4．9％，0；总有效率为95．1％。结论PVP可有效地缓解骨质疏松性压缩骨折引起的疼痛。

Percutaneous vertebroplasty for treatment of osteoporotic vertebral fracture

Objective To investigate the clinical effectiveness of percutaneous vertebroplasty(PVP)in the treatment of osteoporotic thoracolumbar vertebral compression fracture.Methods From Feb.2003 to Dec.2005,under C-arm fluoroscopy monitoring,45 consecutive PVP procedures through unilateral or bilateral verterbral pedicles with methylmethacrylate polymer(PMMA)were performed on 41 patients with painful osteoporotic thoracolumbar vertebral compression fracture.Results The technical success rate of PVP was 100%.The average injection dose of PMMA was 4 ml for thoracic and 5 ml for lumbar vertebrae.Cement leakage occurred during the procedure at 7 levels.The patients were followed for 3-12 monthes.CR,PR,MR and NR were 56.1%,39.0%,4.9% and 0 respectively,with a total effective rate of 95 %.There was no severe complication related to this treatment.Conclusion PVP is safe and effective,and has a useful role in the treatment of osteoporotic vertebral compressed fractures.