Critical pressure for capillary valves in a Lab-on-a-Disk: CFD and flow visualization

Capillary valves are used as pressure barriers to control flow sequencing in microfluidic devices. Influence of valves height on liquid flow pattern and critical pressure are studied through flow visualization and CFD predictions (Gambit® 2.2.30 and FLUENT® 6.2.16). Both hydrophilic and hydrophobic walls are studied. Results show that the surface tension plays a major role in the liquid progress through the microchannel/valve and also in the valve filling process. Critical pressure varies linearly with the valve hydraulic diameter in the range 0.91 < D_h < 3.5 mm] according to: P = 14.14 · D_h + 47.42 Pa].