山茱萸化学成分及药理作用研究新进展

山茱萸临床应用广泛,具有多种药理作用,针对近年来山茱萸的化学成分、药理作用研究情况进行综述。发现山茱萸中的主要药效成分为环烯醚萜及其苷、三萜、黄酮、鞣质、有机酸、多糖等,目前针对山茱萸化学成分的研究多集中在环烯醚萜及其苷、三萜及多糖类。山茱萸可以作用在机体的多个方面,但主要作用集中在免疫系统、循环系统、神经系统及泌尿系统,具有抗肿瘤、保护心肌、降血糖、调节骨代谢、保护神经元、抗氧化、保护肝脏、调控视黄醇、抗衰老、抗炎等多种药理作用。

New Progress in Chemical Constituents and Pharmacological Action of Cornus officinalis

Cornus officinalis is widely used in clinic,it has many kinds of pharmacological effects.The literatures of rencent years on the chemical constituents and pharmacological effects of Cornus officinalis were reviewed.It was found that the main effective constituents of Cornus officinalis were iridoid and its glycosides,triterpenoids,flavonoids,tannins,organic acids and polysaccharides,and the research on the chemical constituents of Cornus officinalis was mainly focused on iridoid and its glycosides,triterpenoids and polysaccharides.Cornus officinalis can be used in many aspects of the body,but its main functions are concentrated in the immune system,circulatory system,nervous system and urinary system.It has many pharmacological effects,such as anti-tumor,myocardial protection,reducing blood sugar,regulating bone metabolism,neuron protection,antioxidant,liver protection,retinol regulation,anti-aging and anti-inflammation.