| 肥胖儿童血清瘦素水平分析 |
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| 引用本文： | 王影,金富国,梁欢.肥胖儿童血清瘦素水平分析[J].中国卫生检验杂志,2011(8). |
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| 作者姓名： | 王影 金富国 梁欢 |
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| 作者单位： | 哈尔滨医科大学附属第三医院; |
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| 摘 要： | 目的:检测肥胖儿童和正常对照儿童血清瘦素水平,探讨瘦素与体重指数、空腹血糖、胰岛素、胰岛素抵抗指数及血脂等的相关性。方法:对100例肥胖儿童及100例正常对照儿童测量身高、体重,计算体重指数(BMI);检测空腹血糖(FPG)、胰岛素(FINS)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A(ApoA)、载脂蛋白B(ApoB);胰岛素抵抗采用稳态模式评估法的胰岛素抵抗指数(HOMA-IR)指标;血清瘦素采用酶联免疫吸附试验检测。结果:肥胖儿童组血清瘦素显著高于正常对照组儿童(P<0.05);血清瘦素与BMI、ALT、TG、LDL-C、APB、FINS、HOMA呈正相关r,值分别为(0.647,0.5840,.328,0.198,0.314,0.5230,.484,P值均<0.05);与HDL-C呈负相关(r=-0.151,P<0.05)。结论:瘦素作为一种脂肪因子,在儿童肥胖的发生中起重要作用。
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| 关 键 词： | 瘦素 肥胖儿童 |
Analysis of leptin level in serum of obese children |
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| WANG Ying,JIN Fu-guo,LIANG Huan.Analysis of leptin level in serum of obese children[J].Chinses Journal of Health Laboratory Technology,2011(8). |
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| Authors: | WANG Ying JIN Fu-guo LIANG Huan |
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| Affiliation: | WANG Ying,JIN Fu-guo,LIANG Huan (The Third Affiliated Hospital of Harbin Medical University,Harbin 150040,China) |
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| Abstract: | Objective:To assay the serum leptin levels in normal control children and obese children,to explore the correlation between leptin and body mass index,fasting plasma glucose,insulin,insulin resistance index,lipids etc.Methods:Of 100 cases of obese children and 100 normal control children,measured height,weight,calculated body mass index(BMI);detected fasting plasma glucose(FPG),insulin(FINS),total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholestero... |
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| Keywords: | Leptin Obese children |
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