乳腺癌术后复发24例临床分析

目的：探讨乳腺癌术后复发的影响因素。方法：回顾性分析2000年-2010年诊治的248例乳腺癌,其中包括24例复发患者的临床资料。结果：原发肿瘤〈5cm和≥5cm的患者复发率分别为6.45%、31.57%;患者腋窝淋巴结转移阴性和阳性的复发率分别为3.77%、16.94%;激素受体阳性和阴性的复发率分别为10.52%、11.76%;规范化疗和未行化疗患者复发率分别为8.82%、50.0%;行规范内分泌治疗和未行内分泌治疗患者复发率分别为6.14%、17.10%,行规范放疗和未行放疗患者复发率分别为2.43%、71.42%。结论：乳腺癌复发与肿瘤大小,淋巴结有无转移以及术后是否规范化疗、放疗和内分泌治疗有显著相关性,而与激素受体情况无显著相关性。

Clinical analysis of 24 recurrent breast cancer after mastectomy

Objective：To investigate the clinical factor of recurrence after mastectomy.Methods：A retrospective study was conducted in 248 patients with breast cancer including 24 cases of recurrences from 2000-2010.Results：The recurrent rates of patients with primary tumor size 5cm and ≥5cm were 6.45%、31.57%;rates of patients with negative axillary nodes and positive axillary nodes were 3.77%,16.94%;rates of patients with positive hormone receptor and negative hormone receptor were 10.52%,11.76%;rates of patients had completed normative chemotherapy and not completed were 8.82%,50.0%;rates of patients had completed normative adjuvant endocrine therapy and not completed were 6.14%,17.10%;rates of patients had completed radiotherapy and not completed were 2.43%,71.42%.Conclusion：The recurrence after mastectomy was positively related to positive axillary nodes,larger primary tumor,adjuvant endocrine therapy,adjuvant chemotherapy and radiotherapy,there was not significant correlation to hormone receptor situation.