血流灌注对高强度聚焦超声消融子宫肌瘤的影响

高强度聚焦超声（HIFU）治疗时，血流灌注会带走部分组织热量。为了保证治疗的安全性和有效性并提高治疗效率，需要在HIFU治疗过程中考虑血流灌注的影响。目前临床治疗已观察到血流灌注会降低HIFU疗效，但针对血流灌注的量化及如何控制血流灌注以提高HIFU疗效仍不明确。本研究以HIFU消融子宫肌瘤为例，分别从血流灌注对HIFU疗效的影响、子宫肌瘤血流灌注的检测、如何控制血流灌注以提高HIFU疗效这几个方面进行综述，旨在明晰血流灌注对HIFU疗效的影响，为临床控制并利用血流灌注提高HIFU疗效提供参考。

Effects of blood perfusion on high-intensity focused ultrasound ablation for uterine fibroids

Abstract: Blood perfusion will take away part of the tissue heat during high-intensity focused ultrasound (HIFU) treatment. In order to ensure the safety and effectiveness of treatment and improve its efficiency, it is necessary to consider the effects caused by blood perfusion during HIFU treatment. At present, it is observed that blood perfusion will reduce the therapeutic effect of HIFU in clinic. However, the quantification of blood perfusion and its contribution mechanism on the therapeutic effect of HIFU are still unclear. Taking HIFU ablation for uterine fibroids as an example, the effect of blood perfusion on the therapeutic effect of HIFU, the detection of blood perfusion in uterine fibroids, and how to control blood perfusion to improve the therapeutic effect of HIFU are summarized in the study, aiming to clarify the effect of blood perfusion on the therapeutic effect of HIFU, and provide a reference for the clinical control and use of blood perfusion to improve the therapeutic effect of HIFU.