Case fatality ratio and mortality rate trends of community-onset Staphylococcus aureus bacteraemia |
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| Affiliation: | 1. University of Calgary, Calgary, AB;2. Vancouver Island Health Authority, Victoria, BC;3. University of Sherbrooke, Sherbrooke, QC, Canada;4. Skaraborg Hospital, SkÖvde, Sweden;5. Canberra Hospital and Australian National University, Canberra, ACT, Australia;6. Aalborg University Hospital and Aalborg University, Aalborg;7. Aarhus University Hospital, Aarhus;8. Hvidovre University Hospital;9. Herlev University Hospital, Copenhagen, Denmark;10. National Institute for Health and Welfare, Helsinki, Finland;11. Royal Inland Hospital, Kamloops, BC, Canada |
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| Abstract: | Lethal outcomes can be expressed as a case fatality ratio (CFR) or as a mortality rate per 100 000 population per year (MR). Population surveillance for community-onset methicillin-sensitive (MSSA) and methicillin-resistant (MRSA) Staphylococcus aureus bacteraemia was conducted in Canada, Australia, Sweden and Denmark to evaluate 30-day CFR and MR trends between 2000 and 2008. The CFR was 20.3% (MSSA 20.2%, MRSA 22.3%) and MR was 3.4 (MSSA 3.1, MRSA 0.3) per 100 000 per year. Although MSSA CFR was stable the MSSA MR increased; MRSA CFR decreased while its MR remained low during the study. Community-onset S. aureus bacteraemia, particularly MSSA, is associated with major disease burden. This study highlights complementary information provided by evaluating both CFR and MR. |
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| Keywords: | Bacteraemia case fatality mortality staphylococcus |
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