| 鲍鱼多糖对荷人鼻咽癌裸鼠抗癌作用的研究 |
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| 引用本文： | 王兵,蒋建敏,许东晖,许实波,邵志宇,林永成.鲍鱼多糖对荷人鼻咽癌裸鼠抗癌作用的研究[J].医学教育探索,2000(8):597-599. |
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| 作者姓名： | 王兵 蒋建敏 许东晖 许实波 邵志宇 林永成 |
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| 作者单位： | [1]深圳海王生物工程有限公司研究发展部 [2]中山大学 |
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| 基金项目： | 国家海洋八六三计划(819)“海洋生物技术”课题资助项目 |
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| 摘 要： | 采用人癌裸鼠移植模型以及电镜观察，对从杂色鲍Ｈａｌｉｏｔｉｓ ｄｉｖｅｒｓｉｃｏｌｏｒ Ｒｅｅｖｅ中提取得到的鲍鱼多糖（ａｂａｌｏｎｅ ｐｏｌｙｓａｃｃｈａｒｉｄｅ，ＡＰ）进行抗肿瘤药理作用研究，结果表明：ＡＰ对裸鼠移植人鼻咽癌具有明显的抑制作用，能明显抑制人鼻咽癌的生长，诱导肿瘤细胞凋亡和坏死，对荷癌裸鼠体重增长无明显抑制作用。
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| 关 键 词： | 鲍鱼多糖 裸鼠 鼻咽肿瘤 中医药疗法 |
Antitumor Effect of Abalone Polysaccharide on Human Nasopharyngeal Cancer Inoculated on Nude Mice |
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| Wang Bing,Jiang Jianmin,Xu Donghui,Xu Shibo,Shao Zhiyu,Lin Yongcheng.Antitumor Effect of Abalone Polysaccharide on Human Nasopharyngeal Cancer Inoculated on Nude Mice[J].Researches in Medical Education,2000(8):597-599. |
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| Authors: | Wang Bing Jiang Jianmin Xu Donghui Xu Shibo Shao Zhiyu Lin Yongcheng |
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| Affiliation: | Shenzhen 518054 |
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| Abstract: | Antitumor effect of abalone polysaccharide (AP) isolated from Haliotis
diversicolor Reeve was studied on nude mice implanted with human nasopharyngeal cancer
cells and investigated under electron microscope. The results showed that AP could
significantly inhibit the growth of implanted cancer cells by inducing cell apoptosis and
necrosis. |
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| Keywords: | abalone polysaccharide (AP) nude mice human nasopharyngeal cancer antitumor effects |
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