| 聚二甲基硅氧烷微流控芯片的制备 |
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| 引用本文： | 李孟春.聚二甲基硅氧烷微流控芯片的制备[J].传感器与微系统,2007,26(9):89-91. |
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| 作者姓名： | 李孟春 |
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| 作者单位： | 太原理工大学,应用物理系,山西,太原,030024 |
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| 摘 要： | 采用印刷电路板技术加工出芯片模具,以聚二甲基硅氧烷(PDMS)为材料制作出微流控芯片。该芯片由基片和盖片组成,微流控沟道位于基片上,深度和宽度分别为75μm和100μm,由盖片对其进行密封。考察了有绝缘漆模具和无绝缘漆模具制作的芯片的电泳分离情况。在该PDMS微流控芯片上对用异硫氰酸酯荧光素标记的氨基酸进行了电泳分离,当信噪比S/N=3时,最小检测浓度达到0.8×10-11mol/L。
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| 关 键 词： | 印刷电路板 制备 微流控芯片 分离 |
| 文章编号： | 1000-9787（2007）09-0089-03 |
| 修稿时间： | 2007-02-07 |
Fabrication of PDMS microfluidic chip |
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| LI Meng-chun.Fabrication of PDMS microfluidic chip[J].Transducer and Microsystem Technology,2007,26(9):89-91. |
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| Authors: | LI Meng-chun |
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| Affiliation: | Department of Applied Physics, Taiyuan University of Technology, Taiyuan 030024, China |
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| Abstract: | The mould of the chip is fabricated with the printed circuit board fabrication technique.Based on the mould,the microfluidic chip is fabricated with PDMS material.The chip is composed of base slab and cover slab,and the microchannel with 75 μm in depth and 100 μm in width is laid on the base slab sealed with the cover slab.The electrophoresis separations of the chips are investigated and the chips are fabricated by using the moulds coated with and without insulation lacquer.The performance of the chip is valuated by the determination of FITC fluorescein-labeled amino acids to a minimum detectable concentration of 0.8×10-11mol/L,when the signal-to-noise-ratio(SNR) S/N is 3. |
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| Keywords: | printed circuit board fabrication microfluidic chip separation |
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