| 内镜下氩离子凝固术联合奥美拉唑治疗Barrett食管76例临床及随访分析 |
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| 引用本文： | 郝丽萍,赖洁莹,司会强,刘青,张小丽,林燕鹏,龚飞跃.内镜下氩离子凝固术联合奥美拉唑治疗Barrett食管76例临床及随访分析[J].胃肠病学和肝病学杂志,2011,20(5):429-431. |
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| 作者姓名： | 郝丽萍 赖洁莹 司会强 刘青 张小丽 林燕鹏 龚飞跃 |
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| 作者单位： | 珠海市第二人民医院消化内科,广东,珠海,519020 |
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| 摘 要： | 目的探讨胃镜下氩离子凝固术联合奥美拉唑治疗Barrett食管的疗效。方法将胃镜检查并病理证实的76例Barrett食管（BE）患者随机分为对照组和治疗组,对照组36例给予口服奥美拉唑20 mg,1次/d;治疗组40例在胃镜下行氩离子凝固术（APC）,术后给予口服奥美拉唑20 mg,1次/d,对于一次治疗不能清除病灶的患者,4周后进行第二次清除,于术后3、6、12个月进行胃镜复查,对其疗效及并发症进行评估。结果对照组在治疗过程中,胃镜下BE长度和范围未见明显改变;至随访结束前,治疗组镜下保持完全清除的BE食管患者占APC治疗的72.5%,治疗组临床缓解率明显高于对照组（P〈0.05）。术后8例出现胸骨后不适,3例出现胸骨后疼痛,3例出现黏膜下气肿,2例出现低热。结论 Barrett食管的内镜下氩离子凝固术安全有效,有良好的临床应用前景。
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| 关 键 词： | 氩离子凝固术 Barrett食管 |
Clinical analysis of argon plasma coagulation combined with omeprazole for treatment of Barrett's esophagus |
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| HAO Liping,LAI Jieying,SI Huiqiang,LIU Qing,ZHANG Xiaoli,LIN Yanpeng,GONG Feiyue.Clinical analysis of argon plasma coagulation combined with omeprazole for treatment of Barrett's esophagus[J].Chinese Journal of Gastroenterology and Hepatology,2011,20(5):429-431. |
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| Authors: | HAO Liping LAI Jieying SI Huiqiang LIU Qing ZHANG Xiaoli LIN Yanpeng GONG Feiyue |
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| Affiliation: | HAO Liping,LAI Jieying,SI Huiqiang,LIU Qing,ZHANG Xiaoli,LIN Yanpeng,GONG FeiyueDepartment of Gastroenterology,Second Municipal People's Hospital,Zhuhai 519020,China |
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| Abstract: | Objective To investigate the effect of argon plasma coagulation combined with omeprazole for treatment of Barrett's esophagus.Methods Seventy-six patients with Barrett's esophagus diagnosed with endoscopy and biopsy were randomly divided into two groups.Control group was treated with 20 mg omeprazole once everyday,and treatment group was treated with argon plasma coagulation combined with omeprazole.If there was residual Barrett's esophagus,argon plasma coagulation was reperformed again after four weeks.All... |
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| Keywords: | Argon plasma coagulation Barrett's esophagus |
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