急性脑梗死患者脑微出血的相关危险因素分析

目的 探讨急性脑梗死（ACI）患者脑微出血（CMB）的相关危险因素,为CMB的预防提供参考.方法 取本院自2011年以来入院的ACI患者84例,均进行MRI磁敏感加权成像（SWI）检查,根据患者有无CMB分为CMB组52例和无CMB组32例.分析2组患者的一般资料及相关临床指标,得出ACI合并CMB的危险因素.结果 CMB组患者年龄显著大于无CMB组,CMB组患者有高血压史、脑卒中史和吸烟史比例显著高于无CMB组;CMB组血HDL水平显著高于无CMB组,血LDL水平显著低于无CMB组,差异均具有统计学意义（P＜0.05）.结论 在ACI患者中,CMB的发生与否与患者年龄、高血压史、脑卒中史和吸烟史以及血HDL、LDL水平直接关联,这对往后临床预测ACI患者发生CMB具有一定的借鉴意义.

Analysis of risk factors associated with cerebral microbleeds in patients with acute cerebral infraction

Objective To analysis the risk factors associated with cerebral microbleeds in patients with acute cerebral in fraction, and to put forward reasonable and effective way to predict the disease. Methods 84 Patients with ACI admitted to hospital were selected since 2011. MRI magnetic susceptibility weighted imaging （SWI） inspection were performed. According to the presence of CMB the patients were divided into the CMB group with 52 cases and the Non-CMB group with 32 cases. The general data and relevent clinical index in two groups were analyzed. And related risk factors of ACI merge into CMB were expected in result. Results Age of patients in CMB group was significantly older than non-CMB group the proportion of pa- tients with history of hypertension, history of stroke, and smoking history in CMB group was significantly greater than that in non-CMB group; serum HDL levels in CMB group were significantly higher than those in non-CMB group, serum LDL levels were significantly lower than those in non-CMB group. The difference of above comparison items were statistically significant （P~0.05）. Conclusion In ACI patients, CMB occurrence is directly associate with age, history of hypertension, smoking history, and history of stroke and serum levels HDL and LDL, which have a certain significance in predicting the occurrence of CMB in patients with ACI.