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夏至草提取物对急性血瘀大鼠淋巴微循环的作用
引用本文:张利民,姜华,刘艳凯,张学锋,牛春雨,张万明.夏至草提取物对急性血瘀大鼠淋巴微循环的作用[J].中药材,2004,27(7):509-511.
作者姓名:张利民  姜华  刘艳凯  张学锋  牛春雨  张万明
作者单位:河北北方学院,张家口,075029
基金项目:河北省中医药管理局科研项目
摘    要:目的:观察夏至草提取物(HLE)对急性血瘀大鼠淋巴微循环的作用.方法:(Dextran)以10ml/kg经静脉注射,1 min注完,诱导大鼠急性血瘀症模型,6 min后治疗组按1.0g/kg(含生药)从颈静脉注射HLE,对照组颈静脉注射等量的生理盐水,通过显微电视录像观察肠系膜微淋巴管(ML)收缩性的变化.结果:夏至草提取物使ML自主收缩频率、收缩活性指数(Index Ⅰ)、总收缩活性指数(IndexⅡ)、淋巴动力学指数(LD-Index)和血压显著高于对照组(P《0.05~0.01).结论:夏至草提取物对急性血瘀大鼠淋巴微循环障碍有非常好的改善作用.

关 键 词:夏至草  血瘀症  淋巴  微循环
修稿时间:2003年11月26

The Effects of Extracts from Herba Lagopsis on Lymph Microcirculation of Acute Blood Stasis Rats
Zhang Limin,Jiang Hua,Liu Yankai,Zhang Xuefeng,Niu Chunyu,Zhang Wanming.The Effects of Extracts from Herba Lagopsis on Lymph Microcirculation of Acute Blood Stasis Rats[J].Jorunal of Chinese Medicinal Materials,2004,27(7):509-511.
Authors:Zhang Limin  Jiang Hua  Liu Yankai  Zhang Xuefeng  Niu Chunyu  Zhang Wanming
Affiliation:Hebei North College, Zhangjiakou 075029.
Abstract:OBJECTIVE: To observe the effects of the extracts from Herba Lagopsis (HLE) on lymph microcirculation of acute blood stasis rats. METHODS: The acute blood stasis model was made by iv dextran (10 ml/kg) within 1 min. After 6 minutes, HLE(1.0g/kg) was given intravenously to the treatment group and the same volume of NS was done in the normal control group. The changes of contractility of mesenteric micro-lymphatics (ML) was observed by using a vital microscope with TV recorder. RESULTS: HLE could markedly improve the ML spontaneous constraction frequency, lymphatics constractive activity (Index I), total lymphatics constractive activity (Index II) and lymphatics dynamics (L. D-Index) (P < 0.05 approximately 0.01). CONCLUSION: HLE played an important role in lymph microcirculation of acute blood stasis rats.
Keywords:Herba Lagopsis  Blood stasis syndrome  Lymph  Microcirculation
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