我院263例药品不良反应报告分析

目的：了解我院药品不良反应（ADR）发生的特点及规律，为临床合理用药提供参考。方法：对我院2008-2009年收集的263例ADR报告，分别从患者年龄、给药途径、涉及药物种类以及临床具体表现等方面进行统计、分析。结果：263例ADR中静脉给药较其他给药途径更易发生ADR（占68．06％）；抗感染药引发ADR居首位（75例，占28．52％），其次是中药制剂（56例，占21．29％），临床表现以皮肤及附件损害最为常见（103例，占39．16％）。结论：应强化ADR监测意识，减少和避免ADR的发生。

Analysis of 263 ADR reports in Jinshan hospital.

Objective： To investigate the characteristics and regular pattern of the adverse drug reactions （ADR） occurred in our hospital for references of clinical rational drug use. Methods： 263 ADR reports collected in our hospital from 2008 to 2009 were analyzed statistically in respect of patients＇ age, route of administration, drug vari- eties and the clinical manifestations. Results： Of the total 263 ADR cases, 68.06% were induced by intravenous administration; anti-infective drugs occupied the first place which caused ADRs in 75 cases （28.52%） followed by chinese patent drugs in 56 cases （21.29%）.The most common clinical manifestations were the damage of skin and adnexa with 39.16% （103cases）.Conclusion- ADR monitoring should be strengthened, reduce or avoid the occur- rence of ADRs.