针刺郄门穴治疗冠状动脉慢血流现象的即刻疗效观察

目的观察针刺郄门穴对冠状动脉慢血流现象(CSFP)患者冠脉流速的即刻作用。方法纳入70例CSFP患者作为研究对象,随机分为试验组(针刺郄门穴)与对照组(针刺假穴位),每组35例。比较两组患者针刺前后冠脉造影下校正的心肌梗死溶栓试验(TIMI)血流帧数计数(CTFC)、中医症状积分的变化情况,同时进行安全性评价。结果(1)针刺前后组内比较,试验组患者的CTFC值下降(P<0.05),对照组CTFC值差异无统计学意义(P>0.05);组间针刺后比较,试验组CTFC差值大于对照组(P<0.05)。(2)针刺前后组内比较,两组患者的中医症状积分均降低(P<0.05);组间针刺后比较,试验组中医症状积分差值大于对照组(P<0.05)。(3)两组患者均未见明显不良反应。结论针刺有助于减轻CSFP患者的自觉症状;与针刺非经非穴相比,针刺郄门穴能加快CSFP患者的冠脉血流,并更好地改善临床不适症状。

Immediate clinical effect of acupuncture at Ximen on the coronary slow flow phenomenon

ObjectiveTo observe the immediate effect of acupuncture at Ximen(PC 4)on coronary flow velocity in patients with coronary slow flow phenomenon(CSFP).MethodsSeventy patients with CSFP were enrolled as study subjects and randomly divided into a test group(acupuncture at Ximen acupoint)and a control group(acupuncture at sham acupoints),with 35 cases in each group. The changes in the corrected Thrombolysis in Myocardial Infarction(TIMI)frame count(CTFC)values under use of coronary angiography and traditional Chinese medicine(TCM)symptom scores were observed and compared before and after acupuncture between the two groups,and safety evaluation was also performed.Results(1) The intragroup comparison showed that after acupuncture the CTFC values in the test group decreased(P<0.05)while the difference of CTFC values in the control group was not statistically significant(P>0.05). After acupuncture,the difference of CTFC values in the test group was higher than that in the control group(P<0.05).(2)After acupuncture,the TCM symptom scores of patients in both groups were lowered(P<0.05);the difference of TCM symptom scores in the test group was higher than that in the control group(P<0.05).(3)No significant adverse reaction was observed in both groups.ConclusionAcupuncture helps to reduce subjective symptoms in patients with CSFP;compared with sham acupuncture,acupuncture at Ximen(PC4)accelerates coronary blood flow and better improves clinical discomfort in patients with CSFP.