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玄丹巴布剂对大鼠乳腺增生病治疗作用的实验研究
引用本文:孟舒,关艳敏,李绍华,鲁明文.玄丹巴布剂对大鼠乳腺增生病治疗作用的实验研究[J].天津中医药,2008,25(5):402-403.
作者姓名:孟舒  关艳敏  李绍华  鲁明文
作者单位:1. 辽宁省计划生育研究院,沈阳,110031
2. 辽宁中医药大学第二附属医院,沈阳,110036
摘    要:目的]观察玄丹巴布剂抑制和治疗乳腺增生病的效果.方法]选用健康雌性大鼠70只,随机分成6组,在乙醚麻醉的无菌条件下做双侧卵巢摘除术,术后肌注庆大霉素0.2 mL/只,连续3 d抗感染后用苯甲酸雌二醇注射液复制乳腺增生病模型.在造模成功后,分别使用玄丹巴布剂外贴乳房部位和乳癖消片灌胃给药,对照观察乳房外观形态、组织学形态和血浆中雌二醇的含量.结果]玄丹巴布剂能抑制大鼠乳腺增生,降低血浆中雌二醇含量.结论]玄丹巴布剂对苯甲酸雌二醇注射液所致的乳腺增生病有一定的治疗作用,可部分地使其恢复正常或减轻其增生程度.

关 键 词:乳腺增生病模型  玄丹巴布剂  实验研究
收稿时间:2008/3/20 0:00:00

Experimental study on therapeutic effect of Xuandan cataplasm in treating hyperplasia of mammary gland
MENG shu,GUAN Yan-min,LI Shao-hua.Experimental study on therapeutic effect of Xuandan cataplasm in treating hyperplasia of mammary gland[J].Tianjin Journal of Traditional Chin Medicine,2008,25(5):402-403.
Authors:MENG shu  GUAN Yan-min  LI Shao-hua
Affiliation:MENG shu1,GUAN Yan-min1,LI Shao-hua2,et al (1. Liaoning Institute of Family Planning,Shenyang 110031,China,2.The Second Hospital Affliated to Liaoning University of TCM,Shenyang 110036,China)
Abstract:Objective] To observe the effect of Xuandan cataplasm on inhibiting and treating hyperplasia of mammary gland(HMG). Methods] Seventy healthy female rats were selected and randomly divided into six groups. HMG was induced by intramuscular injection of benzoate estradiol in female ovariectomized rats with. Xuandan cataplasms and Rupixiao tablets were put on the breast. The outside appearance and histological structure of the breast and the content of dihydrotheelin in plasma were compared and observed. Res...
Keywords:hyperplasia of mammary gland  Xuandan cataplasm  experimental research  
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