妊娠合并病毒性肝炎96例分析

目的 分析妊娠合并病毒性肝炎（妊娠期肝炎）的发病特点。方法回顾性分析96例妊娠期肝炎患者的临床资料，并与同期育龄非妊娠病毒性肝炎比较，比较她们的病因、肝功能生化指标改变及发病的临床特点。结果妊娠期肝炎以乙型为主，随妊娠周数增加，肝炎发病率增加，妊娠期肝炎凝血酶原时间（PT）明显延长，白蛋白（ALB）显著降低，并发肝性脑病和肝肾综合征均高于非妊娠肝炎组，妊娠期肝炎组重型肝炎发生率高于非妊娠肝炎组（P〈0．05）。结论妊娠期肝炎临床特点与非妊娠病毒性肝炎有所不同．患者的处理需视不同的病程、病情采取相应的措施．

The analysis of pregnancy with virus hepatitis

Objective To analyse the pathogeny of pregnancy with virus hepatitis,the change of index of hepatic function and the clinical pathogenetic characteristic,and to explore the relationship between pregnancy and hepatitis.Methods The clinical datas of 96 pregnant patients with virus hepatitis were retrospectively analyzed,and compared with non-pregnancy during the reprodective age in the corresponding period.The pathogeny,index of hepatic function and clinical pathogenetic characteristic were compared.Results Virus hepatitis in the pregnancy were mostly type B hepatits,the morbility of hepatitis increased gradually along with the progress of pregnant weeks,the prothrombin time(PT) significantly prolonged in pregnancy with virus hepatitis,and the albumin decreased significantly,the complications of hepatocerebral disease and hepatorenal syndrome were more than non-pregnancy with virus hepatits,the incidence rate of serious hepatiti was higher than non-pregnancy with virus hepatitis(P<0.05).Conclusion The clinical pathogenetic characteristic of pregnancy with virus hepatitis is different with non-pregnancy with virus hepatits,the treatment requires different measures according to the different course of disease and pathogenetic condition.