| 用于免疫微传感器的CMOS微弱电流读出电路 |
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| 引用本文： | 李策, 杨海钢, 夏善红, 边超,.用于免疫微传感器的CMOS微弱电流读出电路[J].电子器件,2006,29(4):1090-1093. |
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| 作者姓名： | 李策 杨海钢 夏善红 边超 |
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| 作者单位： | 1. 中国科学院电子学研究所,传感技术联合国家重点实验室,北京,100080;中国科学院研究生院,北京,100039
2. 中国科学院电子学研究所,传感技术联合国家重点实验室,北京,100080 |
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| 摘 要： | 分析了传感器微电极产生信号的特点，阐述了读出电路的工作原理和设计要点，采用电流转换为时间的方法实现了弱信号的读出，最小可测量1pA的直流。电流，量程达5个数量级，相对误差小于0．1。并且系统自带10位数字信号输出，避免了使用AD转换器带来的功率和空间的消耗。系统采用Chartered 0．35um标准CMOS工艺流片。
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| 关 键 词： | 安培型 免疫传感器 微弱电流检测 读出电路 |
| 文章编号： | 1005-9490（2006）04-1090-04 |
| 收稿时间： | 2005-02-20 |
| 修稿时间： | 2005-02-20 |
CMOS Weak Current Readout Circuit for Amperometric Immunosensor |
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| LI Ce.CMOS Weak Current Readout Circuit for Amperometric Immunosensor[J].Journal of Electron Devices,2006,29(4):1090-1093. |
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| Authors: | LI Ce~ |
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| Affiliation: | 1. State Key Lab of Transducer Technology, Institute of Electronics, Beijing 100080, China; 2. Graduate School of Chinese Academy of Sciences, Beijing 100039, China |
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| Abstract: | The characterist ics o f the signal f rom the sensor?? s microelect ro des are analyzed. A w eak cur rent
readout circuit is designed, w hich uses a method of t ransfer ring current signal into t ime one. Curr ent ran??
g ing f rom 1 pA to 100 nA can be measured w ith a max imum relat iv e deviat ion of 0. 1. T he system also de??
l iv ers a 10 bit dig ital o utput , w hich avoids use of an ex tr a analog??to??digital converter. T his w ay, pow er
and space of the chip can be further reduced. The chip has been fabricated in the 0. 35 ??m Chartered CMOS
pro cess. Ex perimental results are r eported, characterising the per formance of the system as an elect ro??
chemical senso r. |
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| Keywords: | amperometric immunosensor weak current readout circuit |
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