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乙二胺四乙酸铁钠口服液治疗小儿缺铁性贫血及对血清微量元素的影响
引用本文:阚淑月,杨建春,于桂兰,王春艳,王秀兰.乙二胺四乙酸铁钠口服液治疗小儿缺铁性贫血及对血清微量元素的影响[J].中国妇幼保健,2009,24(6).
作者姓名:阚淑月  杨建春  于桂兰  王春艳  王秀兰
作者单位:河北省唐山市妇幼保健院,063000
基金项目:河北省科学技术研究与发展指导计划
摘    要:目的:探讨乙二胺四乙酸铁钠(NaFeEDTA)口服液治疗婴幼儿缺铁性贫血的疗效及其对血清微量元素的影响。方法:对101例缺铁性贫血(IDA)患儿给予NaFeEDTA口服液0.5mg·kg-1·d-1,连服8周,治疗前、后分别测定血常规和微量元素,并与正常儿童进行对照。结果:用药8周后93.0%的IDA患儿血红蛋白(Hb)恢复至正常水平(P<0.01);治疗前IDA患儿血清铁、锌、铜均较正常儿童低(P<0.05),治疗8周后血清铁、锌、铜均较治疗前明显升高(P<0.05),血清钙、镁变化不明显。结论:NaFeEDTA口服液治疗婴幼儿IDA临床效果好,可显著升高血清铁、锌、铜水平。

关 键 词:缺铁性贫血  NaFeEDTA  疗效  微量元素

Effects of NaFeEDTA liquid on the treatment of iron deficiency anemia and the levels of trace elements in serum in children
Abstract:Objective:To explore the effects of NaFeEDTA liquid on the treatment of iron deficiency anemia and the levels of trace elements in serum in children.Methods:101 children with iron-deficiency anemia were treated with NaFeEDTA liquid for 8 weeks,0.5 mg·kg-1·d-1.The levels of trace elements in serum and routine analysis of blood were detected before and after treatment and compared to healthy children.Results:The recovery rate of hemoglobin was 93% after treatment(P<0.01).Before treatment the levels of serum iron,zinc and copper were lower than those in the healthy children(P<0.05).The levels of serum iron,zinc and copper after treatment were significantly higher than those before treatment(P<0.05),NaFeEDTA liquid had no effect on serum levels of calcium and magnesium.Conclusion:The effect of NaFeEDTA liquid is prominent,which can increase the levels of serum iron,zinc and copper remarkably.
Keywords:NaFeEDTA
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