药品不良反应及安全用药知识在某三甲医院三类医务人员中认知度研究

目的：研究了解医师、护师、药师三类医务人员对药品不良反应（ADR）以及安全用药相关知识的认知情况，为ADR及临床安全用药监测的深入开展提供参考。方法：利用网上药学问卷调查平台对皖南地区某大型三级甲等医院45个临床科室的医务人员（医师、护师、药师）的ADR以及安全用药相关知识进行网上调查，数据由平台自动导出Excel表格，使用SPSS19．0软件进行统计分析。结果：通过调查平台，获取有效调查问卷575份，医务人员对ADR和安全用药知识的平均知晓率为83．0％，对ADR上报流程平均知晓率为83．4％。三类医务人员（医生、护师、药师）对于“什么是ADR”、“用药错误的含义”等基本概念的知晓程度较高，回答无明显差异（P〉0．05）。对于“药品不良反应／不良反应事件（ADR／ADE）”、“用药错误”的判断，回答存在显著差异（P〈0．001），医师、护师的知晓程度低于药师。对于“用药后出现ADR的应对措施”、“ADR必须填写的项目”等问题，三类医务人员（医生、护师、药师）问题差异无统计学意义（P〉0．05），但对于“ADR上报期限”等的回答有显著差异（P〈0．001），药师的知晓率高于医师、护师。结论：综合分析该院三类医务人员对ADR和安全用药基本知识掌握总体较好，但对于ADR与ADE、用药错误等概念之间差别存在混淆。应以多种形式对医务人员的ADR和安全用药相关知识进行培训、教育，提高医务人员对ADR／ADE、用药错误等的判断能力，加强ADR监测水平和上报意识，提升合理用药水平，保障患者用药安全。

Study on awareness of adverse knowledge among three kinds of hospital drug reactions and Safe Drug Use medical stuff in a certain 3A-grade

AIM： To study the awareness of adverse drug reactions and Safe Drug Use knowledge in doctors, nurses, and pharmacists these three kinds of medical staff, thus provi- ding reference for the development of adverse drug reaction and the clinical Safe Drug Use mo- nitoring in depth. METHODS： We made a sur- vey of questionnaire on the ADR and the Safe Drug Use knowledge, in medical personnel （doctors, nurses, pharmacists） from 45 clinical de- partments of a large 3A-Grade hospital in Anhui south region, by online survey conducted with online pharmacy survey platform. Data from the platform were derived form excel automatically, statistical analysis was performed using SPSS 19.0 software. RESULTS： The survey platform obtained 575 valid questionnaires. The average rate of awareness of medical staff on ADR and Safe Drug Use was 83.0%, and 83.4% on processes of reporting ADR. There were good awareness rate in medical personnel （doctors, nurses, pharmacists） on the basic concept of ad- verse drug reactions, medication errors, no sig- nificant difference was observed （P 〉 0.05）. However, the awareness rate on judgment of ADR / ADE, medication error was different sig nificantly （P〈0. 001）. The level of awareness of doctors, nurse was lower than that of phar- macists. On ＂countermeasures for treatment e- mergent ADR＂, ＂mandatory items in reporting ADR＂, there were no significant difference in types of medical personnel （P〈0.05）, howev- er, they were different on answers to the stated time limit for ADR report （p ~ 0. 001）, The awareness pharmacists was higher than the doc tors and nurses. CONCLUSION： Comprehensive analysis demonstrate the level of three types of hospital staff is good overall, on the basic knowledge on the ADR and Safe Drug Use, but there are some concepts confusion on adverse drug reactions, adverse events, medication er- rors as well. Medical staff should improve knowledge of ADR and Safe Drug Use by various forms of training, education, as well as the judgment of the medical staff on ADR/ADE, medication errors, the level of ADR monitoring and reporting, so as to improve the level of ra- tionality of medicine and safety.