| 乳腺分泌脂质性癌临床病理分析 |
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| 引用本文： | 怀建国,司有谊,蒋艳,杨小苗,汪谟庆,芮景. 乳腺分泌脂质性癌临床病理分析[J]. 临床与实验病理学杂志, 2009, 25(1) |
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| 作者姓名： | 怀建国 司有谊 蒋艳 杨小苗 汪谟庆 芮景 |
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| 作者单位： | 芜湖市第一人民医院病理科,241000;皖南医学院附属弋矶山医院普外科,芜湖,241001;芜湖市第一人民医院病理科,241000;皖南医学院附属弋矶山医院普外科,芜湖,241001 |
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| 摘 要： | 目的 探讨乳腺分泌脂质性癌(breast lipid-secreting carcinoma)临床病理特征.方法 对3例进行病理组织学观察、特殊染色PAS、AB染色和免疫组化标记ER、PR、Ki-67、c-erbB-2、p53等.结果 3例均为女性,年龄分别为44、54、50岁,均可触及乳腺肿块,肿瘤境界欠清楚,镜下肿瘤边缘呈浸润性生长,肿瘤主要由空泡状细胞即组织细胞样细胞和其它少量皮脂腺样细胞、大汗腺样细胞组成.AB、PAS染色阴性.免疫组化(SP法)瘤细胞示:ER、PR阴性、c-erbB-2、Ki-67、p53不同程度阳性.3例均术中快速切片诊断癌后,行乳腺改良根治手术.结论 乳腺分泌脂质性癌是一种相对少见,恶性度较高,预后较差的肿瘤,诊断主要依靠病理组织检查及特殊染色.免疫标记可帮鉴别诊断及判断预后.
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| 关 键 词： | 乳腺肿瘤 分泌脂质性癌 免疫组织化学 |
Clinicopathological analysis of breast lipid-secreting carcinoma |
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| HUAI Jian-guo,SI You-yi,JIANG Yan,YANG Xiao-miao,WANG Mo-qing,RUI Jing. Clinicopathological analysis of breast lipid-secreting carcinoma[J]. Chinese Journal of Clinical and Experimental Pathology, 2009, 25(1) |
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| Authors: | HUAI Jian-guo SI You-yi JIANG Yan YANG Xiao-miao WANG Mo-qing RUI Jing |
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| Affiliation: | 1Department of Pathology;Wuhu First People's Hospital;Wuhu 241000 China;2Department of Surgery;Yijishan Hospital;Wannan Medical College;Wuhu 241001;China |
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| Abstract: | Purpose To study the clinical pathological features of breast lipid-secreting cacinoma.Methods Three cases of breast lipid-secreting cacinoma were studied by using light microscopy and PAS,AB histochemical staining.Immunohistochemistry was used to detect the expression of ER,PR,Ki-67,c-erbB-2 and p53.Results All the three cases occurred in women,with age ranged from 44 to 54 years.All patients presented with palpable tumors.The tumors showed histocytoid type,sebaceous type and apocrine type.AB and PAS stain... |
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| Keywords: | breast neoplasms lipid-secreting carcinoma immunohistochemistry |
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