| 早期应用东菱克栓酶对沙鼠出血性脑梗塞的影响 |
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| 引用本文： | 吴继敏,丁德云.早期应用东菱克栓酶对沙鼠出血性脑梗塞的影响[J].临床神经病学杂志,1997,10(4):210-212. |
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| 作者姓名： | 吴继敏 丁德云 |
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| 作者单位： | 浙江医科大学附属第二医院心脑血管研究所 |
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| 摘 要： | 以沙鼠左侧前脑缺血再灌注为动物模型，研究早期东菱克栓酶（ＤＦ－５２１）对并发出血及梗塞面积的影响。发现早期（６小时内）使用ＤＦ－５２１并不增加出血危险性，同时可降低视交叉平面梗塞面积。提示沙鼠脑梗塞起病６小时内，应用ＤＦ－５２１进行溶栓治疗是安全的。
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| 关 键 词： | 东菱克栓酶 溶栓 出血性脑梗塞 |
The effect of early use of batroxobin(DF 521) on hemorrhagic infarction in gerbil |
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| Wu Jimin,Ding Deyun.Cardio Cerebrovascular institute,Zhejiang Medical University,Hang Zhou.The effect of early use of batroxobin(DF 521) on hemorrhagic infarction in gerbil[J].Journal of Clinical Neurology,1997,10(4):210-212. |
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| Authors: | Wu Jimin Ding DeyunCardio Cerebrovascular institute Zhejiang Medical University Hang Zhou |
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| Affiliation: | Wu Jimin,Ding Deyun.Cardio Cerebrovascular institute,Zhejiang Medical University,Hang Zhou 310009 |
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| Abstract: | The effect of DF 521 on hemorrage and infarction area in a gerbil ischemic reperfusion model were studied. We found that early use of DF 521(within 6 hr) would not increase the risk of hemorrage,on the other hand, it could decrease the infarction area of gerbil brain. The results indicated that the thrombolysis within 6 hr is a safe theraputic procedure in gerbil. |
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| Keywords: | DF 521 Thrombolysis Hemorrhagic cerebral infarction |
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