| 安胃降逆饮对大鼠胃功能的影响 |
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| 引用本文： | 宋建徽,孟祥琴,苏素文,郭鸣放,王川,苗庆峰,任雷鸣.安胃降逆饮对大鼠胃功能的影响[J].河北医科大学学报,2000,21(4):202-204. |
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| 作者姓名： | 宋建徽 孟祥琴 苏素文 郭鸣放 王川 苗庆峰 任雷鸣 |
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| 作者单位： | 河北医科大学基础医学院药理学教研室,石家庄,050017 |
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| 摘 要： | 目的 观察安胃降逆饮对胃功能的影响，分析其镇吐作用机制。方法 采用大鼠离体胃条法测定胃条张力，小鼠粉红排空试验法测定胃排空量和０．１ｍｏｌ／Ｌ ＮａＯＨ滴定法测定胃酸含量。结果安胃降逆饮对大鼠胃肌物基础张力和乙酰胆碱引起的痉挛性收缩有明显抑制作用（Ｐ〈０．０１），对小鼠胃排空，大鼠胃液量，胃液酸度及总酸度无明显影响（Ｐ〉０．０５）。结论 安胃降逆饮的镇吐作用至少部分是通过抑制胃肠平滑肌蠕动而发挥作
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| 关 键 词： | 胃肠活动 安胃降逆饮 胃排空 胃功能 实验研究 |
EFFECTS OF ANWEI JIANGNI YIN ON GASTRIC FUNCTION IN RATS |
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| Song Jianhui,Meng Xiangqin,Su Suwen,Guo Mingfang,Wang Chuan,Miao Qingfeng,Ren Leiming.EFFECTS OF ANWEI JIANGNI YIN ON GASTRIC FUNCTION IN RATS[J].Journal of Hebei Medical University,2000,21(4):202-204. |
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| Authors: | Song Jianhui Meng Xiangqin Su Suwen Guo Mingfang Wang Chuan Miao Qingfeng Ren Leiming |
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| Abstract: | ObjectiveTo observe the effects of Anwei Jiangni Yin on gastric function.MethodsThe isolated gastric strips of in rats were used to measure the gastric tension,and the phenol red excretion test was applied to determine the volume of gastric evacuation,and NaOH 0.1 mol/L titrimetry was used to measure the gastric acid of the rat.ResultsAnwei Jiangni Yin obviously reduce the base tension of the gastric muscle and the spasmotic contraction caused by acetylcholine(P< 0.01 ).It had no obviously effects on the gastric evacuation in rats,no effect on the volume of gastric juice,gastric acidity and the total acidity(P> 0.05 ).ConclusionThe antiemetic effect of Anwei Jiangni Yin is attributed to inhibtion of gastric function. |
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| Keywords: | Chinese herb antiemetic/pharmacol gastrointestianal motility gastric emptying rats mice |
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