| HPLC法测定通窍鼻炎片中木兰脂素的含量 |
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| 引用本文： | 许文东,张国锋,周美丽.HPLC法测定通窍鼻炎片中木兰脂素的含量[J].齐鲁药事,2006,25(10):599-600. |
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| 作者姓名： | 许文东 张国锋 周美丽 |
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| 作者单位： | 山东齐都药业有限公司,淄博,255400 |
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| 摘 要： | 目的建立HPLC法测定通窍鼻炎片中木兰脂含量的分析方法。方法用Phenomenex C18色谱柱(250mm×4.6mm,5μm),乙腈-四氢呋喃-水(35∶1∶64)作为流动相,流速为1.0ml.min-1,检测波长为274nm。结果木兰脂素在0.2~2.0μg与峰面积线性关系良好(r=0.9999),平均回收率为99.77%,RSD=1.048%(n=5)。结论方法操作简便、重现性好、灵敏度高、专属性强,可用于通窍鼻炎片的质量控制。
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| 关 键 词： | 木兰脂素 通窍鼻炎片 高效液相色谱法 |
| 文章编号： | 1672-7738（2006）10-0599-02 |
Determination of magnolin in Tongqiaobiyan Tablets by HPLC |
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| XU Wen-dong,ZHANG Guo-feng,ZHOU Mei-li.Determination of magnolin in Tongqiaobiyan Tablets by HPLC[J].qilu pharmaceutical affairs,2006,25(10):599-600. |
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| Authors: | XU Wen-dong ZHANG Guo-feng ZHOU Mei-li |
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| Abstract: | OBJECTIVE To establish an HPLC method for determination of magnolin in Tongqiaobiyan Tablets.METHODS The HPLC method was performed on Phenomenex C_(18) column,acetonitrile-tetrahydrofuan-water(35∶1∶64)as mobile phase,the flow rate was 1.0ml·min~(-1),and detection wavelength was set at 274nm.RESULTS The liner rang of magnolin was 0.2～2.0μg(r=0.9999),the average recovery was 99.77% with RSD=1.048%(n=5).CONCLUSION The method was simple,highly repeatable,highly sensitive and specific,and can be used for quality control of Tongqiaobiyan Tablets. |
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| Keywords: | Magnolin Tongqiaobiyan Tablets HPLC |
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