国人正常角膜非球面性特征及其年龄的相关性改变

目的 探讨和分析国人正常角膜前表面的非球面特性及其与年龄的相关性.方法 按照入选标准序贯选取年龄在11～50周岁、屈光度数为+0.50～-3.00D且散光<1.00D的受检者123人,平均年龄(29.58±11.8)岁.根据受检者的年龄,每十年为一组,共分4组:11～20岁组、21～30岁组、31～40岁组和41～50岁组.采用鹰视角膜地形图仪进行角膜Q值的测量,每位受检者只取其中1只眼数据进行统计,分别分析每眼角膜前表面距中央10°、15°、20°、25°、30°范围的Q值.结果国人11～50周岁平均Q10、Q15、Q20、Q25和Q30分别为-0.08±0.09、-0.12±0.1、-0.14±0.11、-0.2±0.11和-0.27±0.11.各年龄组间Q25与Q30差异有统计学意义(Q25:P =0.045;Q30:P =0.012),41～50岁组角膜非球面性比21～30岁组明显(P < 0.05).Q15和Q20与年龄呈负相关(Q15:r =-0.202,P =0.025;020:r =-0.214,P =0.018),Q10、Q25、030与年龄无明显相关性(P > 0.05).结论 国人正常角膜6mm区平均Q值为-0.14,不同年龄的角膜Q值存在着一定的差异,随着年龄的增大,角膜非球面性更明显.

Age-related changes of corneal asphericity in Chinese population

Objective To investigate the corneal asphericity of Chinese eyes at different ages. Methods One hundred and twenty-three eyes of l23 normal subjects(age range from 11-50 years old),average(29.58±11.8 years old)were examined. The range of spherical equivalent error is from +0.50D to -3.00D,and the astigmatism of all eyes was less than 1.00D. Patients were divided into four age groups: 11 to 20 years(group1),21 to 30 years(group 2),31 to 40 years(group 3)and 41 to 50 years(group 4). Corneal asphericity was measured using ALLEGRO Topolyzer. Results The Q10,Q15,Q20,Q25 and Q30 was -0.08±0.09,-0.12±0.1,-0.14±0.11,-0.2±0.11 and -0.27 ±0.11 respectively. The differences of Q20 and Q30 were significant among the four groups(Q25:P=0.045,Q30:P=0.012). The corneal asphericity in group 4 is higher than group 2(P<0.05),Q15(r =-0.202,P=0.025)and Q20(r =-0.214,P=0.018)were correlated with age adversely. Conclusions The Q value of Chinese eyes was -0.14(6mm area). There was small difference between ages in corneal asphericity. Corneal asphericity is more obviously with age increase.